Evidence map›Paper›PMID 36499522›Full record

ReviewInternational journal of molecular sciences2022

The Role of Circular RNAs in the Physiology and Pathology of the Mammalian Ovary.

Jinbi Zhang, Caixia Wang, Chao Jia, Yi Zhang, Xinxin Qing, Yuge Zhang, Jingge Liu, Shiyong Xu, Zengxiang Pan

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
3.2field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 38 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Food science & nutrition · 2025
    Article
  10. Article
  11. CircTEC Inhibits the Follicular Atresia in Buffalo (International journal of molecular sciences · 2024
    Article
  12. Article
  13. Review
  14. Circular RNAs: characteristics, functions, mechanisms, and potential applications in thyroid cancer.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2024
    Review
  15. Review
  16. Article
  17. Biomarkers in Polycystic Ovary Syndrome.Current opinion in physiology · 2023
    Article
  18. Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Jinbi ZhangCollege of Animal Science and Food Engineering, Jinling Institute of Technology, Nanjing 211169, China.ORCID 0000-0002-9492-3425
Caixia WangCollege of Animal Science and Technology, Nanjing Agricultural University, Nanjing 210095, China.
Chao JiaCollege of Animal Science and Technology, Nanjing Agricultural University, Nanjing 210095, China.
Yi ZhangCollege of Animal Science and Technology, Nanjing Agricultural University, Nanjing 210095, China.ORCID 0000-0001-8358-1223
Xinxin QingCollege of Animal Science and Technology, Nanjing Agricultural University, Nanjing 210095, China.
Yuge ZhangCollege of Animal Science and Technology, Nanjing Agricultural University, Nanjing 210095, China.
Jingge LiuCollege of Animal Science and Food Engineering, Jinling Institute of Technology, Nanjing 211169, China.
Shiyong XuCollege of Animal Science and Food Engineering, Jinling Institute of Technology, Nanjing 211169, China.
Zengxiang PanCollege of Animal Science and Technology, Nanjing Agricultural University, Nanjing 210095, China.
Nanjing Agricultural University · CNJinling Institute of Technology · CN

Funding

National Natural Science Foundation of China 31902123 & 31672421&32002175Scientific Research Fund of Jinling Institute of Science and Technology 205/040521400182
6 · The paper itself

Abstract

Circular RNAs (circRNAs) are an abundant class of endogenous non-coding RNAs (ncRNAs) generated from exonic, intronic, or untranslated regions of protein-coding genes or intergenic regions. The diverse, stable, and specific expression patterns of circRNAs and their possible functions through cis/trans regulation and protein-coding mechanisms make circRNA a research hotspot in various biological and pathological processes. It also shows practical value as biomarkers, diagnostic indicators, and therapeutic targets. This review summarized the characteristics, classification, biogenesis and elimination, detection and confirmation, and functions of circRNAs. We focused on research advances circRNAs in the mammalian ovary under conditions including ovarian cancer, polycystic ovarian syndrome (PCOS), and maternal aging, as well as during reproductive status, including ovarian follicle development and atresia. The roles of circRNAs in high reproductive traits in domestic animals were also summarized. Finally, we outlined some obstructive factors and prospects to work with circRNA, aiming to provide insights into the functional research interests of circRNAs in the reproduction and gynecology areas.

Indexed as

Polycystic Ovary SyndromeRNA, CircularAnimalsExonsFemaleHumansIntronsMammalsRNA, CircularatresiacircRNAsfollicle developmentovary

Identifiers

PMID36499522
PMCPMC9737273
OpenAlexW4310675977

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.