Evidence map›Paper›PMID 36499487›Full record

ArticleInternational journal of molecular sciences2022

Bromodomain Protein BRD4-Mediated Mutant p53 Transcription Promotes TNBC Progression.

Julie Xia Zhou, Ewud Agborbesong, Linda Xiaoyan Li, Xiaogang Li

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 18 citations in OpenAlex.

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  9. Downregulation of EZH2 Promotes Renal Epithelial Cellular Senescence and Kidney Aging.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2025
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Julie Xia ZhouDepartment of Internal Medicine, Mayo Clinic, Rochester, MN 55905, USA .
Ewud AgborbesongDepartment of Internal Medicine, Mayo Clinic, Rochester, MN 55905, USA .
Linda Xiaoyan LiDepartment of Internal Medicine, Mayo Clinic, Rochester, MN 55905, USA .
Xiaogang LiDepartment of Internal Medicine, Mayo Clinic, Rochester, MN 55905, USA .
WinnMed · USMayo Clinic · US

Funding

The crosstalk of DNA and lysine methyltransferases in ADPKD.R01DK126662 · NIDDK · MAYO CLINIC ROCHESTER · PI Xiaogang Li · 2020 to 2026
$3.0M
ADPKD: Understanding immunosuppression mechanisms and discovering treatmentR01DK129241 · NIDDK · MAYO CLINIC ROCHESTER · PI LI, XIAOGANG · 2021 to 2024
$1.8M
NIDDK NIH HHS R01 DK126662NIDDK NIH HHS R01 DK129241NIH HHS DK129241, DK126662
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Triple Negative Breast NeoplasmsAzepinesBromodomain Containing ProteinsCell Cycle ProteinsCell Line, TumorCell ProliferationHumansNuclear ProteinsTranscription FactorsTriazolesTumor Suppressor Protein p53AzepinesBRD4 protein, humanBromodomain Containing ProteinsCell Cycle ProteinsNuclear ProteinsTranscription FactorsTriazolesTumor Suppressor Protein p53BRD4p53triple-negative breast cancer

Identifiers

PMID36499487
PMCPMC9738555
OpenAlexW4311103803

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.