Evidence map›Paper›PMID 36499466›Full record

ArticleInternational journal of molecular sciences2022

Isolation of TTF-1 Positive Circulating Tumor Cells for Single-Cell Sequencing by Using an Automatic Platform Based on Microfluidic Devices.

Hei-Jen Jou, Hsin-Cheng Ho, Kuan-Yeh Huang, Chen-Yang Chen, Sheng-Wen Chen, Pei-Hsuan Lo, Pin-Wen Huang, Chung-Er Huang, Ming Chen

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.5field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 1 country.

Hei-Jen JouDepartments of Obstetrics and Gynecology, Taiwan Adventist Hospital, Taipei 105404, Taiwan.
Hsin-Cheng HoCytoaurora Biotechnologies Inc., Hsinchu Science Park, Hsinchu 302058, Taiwan.
Kuan-Yeh HuangCytoaurora Biotechnologies Inc., Hsinchu Science Park, Hsinchu 302058, Taiwan.ORCID 0000-0002-1730-9587
Chen-Yang ChenCytoaurora Biotechnologies Inc., Hsinchu Science Park, Hsinchu 302058, Taiwan.ORCID 0000-0001-9568-2152
Sheng-Wen ChenCytoaurora Biotechnologies Inc., Hsinchu Science Park, Hsinchu 302058, Taiwan.ORCID 0000-0002-1848-0108
Pei-Hsuan LoDepartments of Obstetrics and Gynecology, Taiwan Adventist Hospital, Taipei 105404, Taiwan.
Pin-Wen HuangDepartment of Emergency Medicine, Show Chwan Memorial Hospital, Changhua 500009, Taiwan.
Chung-Er HuangCytoaurora Biotechnologies Inc., Hsinchu Science Park, Hsinchu 302058, Taiwan.
Ming ChenDepartment of Genomic Medicine, Changhua Christian Hospital, Changhua 500209, Taiwan.ORCID 0000-0001-5076-2917
Chang Bing Show Chwan Memorial Hospital · TWDayeh University · TWNational Chung Cheng University · TWNational Taipei University of Nursing and Health Science · TWTaiwan Adventist Hospital · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Single-cell sequencing provides promising information in tumor evolution and heterogeneity. Even with the recent advances in circulating tumor cell (CTC) technologies, it remains a big challenge to precisely and effectively isolate CTCs for downstream analysis. The Cell Reveal

Indexed as

Lung NeoplasmsNeoplastic Cells, CirculatingCell Line, TumorCell SeparationHumansLab-On-A-Chip Devicesautomatic cell pickercirculating tumor cellsEGFRERBB2KRASlung cancernanostructured microfluidic chipsingle-cell sequencingSTK 11TTF-1+ CTCs

Identifiers

PMID36499466
PMCPMC9736518
OpenAlexW4311160667

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.