Evidence map›Paper›PMID 36499450›Full record

ReviewInternational journal of molecular sciences2022

Evolution of Treatment in Advanced Cholangiocarcinoma: Old and New towards Precision Oncology.

Maurizio Capuozzo, Mariachiara Santorsola, Loris Landi, Vincenza Granata, Francesco Perri, Venere Celotto, Oreste Gualillo, Guglielmo Nasti, Alessandro Ottaiano

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
4.4field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 20 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Maurizio CapuozzoCoordinamento Farmaceutico, ASL-Naples-3, 80056 Ercolano, Italy.
Mariachiara SantorsolaIstituto Nazionale Tumori di Napoli, IRCCS "G. Pascale", Via M. Semmola, 80131 Naples, Italy.
Loris LandiSanitary District, Ds. 58 ASL-Naples-3, 80056 Ercolano, Italy.
Vincenza GranataIstituto Nazionale Tumori di Napoli, IRCCS "G. Pascale", Via M. Semmola, 80131 Naples, Italy.ORCID 0000-0002-6601-3221
Francesco PerriIstituto Nazionale Tumori di Napoli, IRCCS "G. Pascale", Via M. Semmola, 80131 Naples, Italy.ORCID 0000-0001-8158-7509
Venere CelottoCoordinamento Farmaceutico, ASL-Naples-3, 80056 Ercolano, Italy.
Oreste GualilloSERGAS (Servizo Galego de Saude) and IDIS (Instituto de Investigación Sanitaria de Santiago), NEIRID Lab (Neuroendocrine Interactions in Rheumatology and Inflammatory Diseases), Research Laboratory 9, Santiago University Clinical Hospital, 15706 Santiago de Compostela, Spain.ORCID 0000-0002-7154-1328
Guglielmo NastiIstituto Nazionale Tumori di Napoli, IRCCS "G. Pascale", Via M. Semmola, 80131 Naples, Italy.
Alessandro OttaianoIstituto Nazionale Tumori di Napoli, IRCCS "G. Pascale", Via M. Semmola, 80131 Naples, Italy.ORCID 0000-0002-2901-3855
Istituto Nazionale Tumori IRCCS "Fondazione G. Pascale" · ITFarmaceutici Damor (Italy) · ITInstituto de Investigación Sanitaria de Santiago · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cholangiocarcinoma (CCA) is a malignant neoplasm arising in the epithelium of the biliary tract. It represents the second most common primary liver cancer in the world, after hepatocellular carcinoma, and it constitutes 10-15% of hepatobiliary neoplasms and 3% of all gastrointestinal tumors. As in other types of cancers, recent studies have revealed genetic alterations underlying the establishment and progression of CCA. The most frequently involved genes are

Indexed as

Bile Duct NeoplasmsCholangiocarcinomaLiver NeoplasmsBile Ducts, IntrahepaticHumansMutationReceptors, Fibroblast Growth FactorReceptors, Fibroblast Growth Factorcholangiocarcinomageneticsivosidenibpemigatinibprecision oncologytarget therapy

Identifiers

PMID36499450
PMCPMC9740631
OpenAlexW4311093194

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.