Evidence map›Paper›PMID 36499415›Full record

ArticleInternational journal of molecular sciences2022

Trifluoromethylcinnamanilide Michael Acceptors for Treatment of Resistant Bacterial Infections.

Tomas Strharsky, Dominika Pindjakova, Jiri Kos, Lucia Vrablova, Pavel Smak, Hana Michnova, Tomas Gonec, Jan Hosek, Michal Oravec, Izabela Jendrzejewska and 2 more

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Tomas StrharskyDepartment of Chemical Drugs, Faculty of Pharmacy, Masaryk University, Palackeho 1946/1, 612 00 Brno, Czech Republic.ORCID 0000-0001-9291-5424
Dominika PindjakovaDepartment of Analytical Chemistry, Faculty of Natural Sciences, Comenius University, Ilkovicova 6, 842 15 Bratislava, Slovakia.
Jiri KosDepartment of Analytical Chemistry, Faculty of Natural Sciences, Comenius University, Ilkovicova 6, 842 15 Bratislava, Slovakia.ORCID 0000-0002-3589-4361
Lucia VrablovaDepartment of Analytical Chemistry, Faculty of Natural Sciences, Comenius University, Ilkovicova 6, 842 15 Bratislava, Slovakia.
Pavel SmakDepartment of Biochemistry, Faculty of Medicine, Masaryk University, Kamenice 5, 625 00 Brno, Czech Republic.ORCID 0000-0001-8610-5601
Hana MichnovaDepartment of Infectious Diseases and Microbiology, Faculty of Veterinary Medicine, University of Veterinary Sciences Brno, Palackeho tr. 1946/1, 612 42 Brno, Czech Republic.
Tomas GonecDepartment of Chemical Drugs, Faculty of Pharmacy, Masaryk University, Palackeho 1946/1, 612 00 Brno, Czech Republic.ORCID 0000-0003-3712-8641
Jan HosekDepartment of Pharmacology and Toxicology, Veterinary Research Institute, Hudcova 296/70, 621 00 Brno, Czech Republic.ORCID 0000-0003-0975-1671
Michal OravecGlobal Change Research Institute CAS, Belidla 986/4a, 603 00 Brno, Czech Republic.ORCID 0000-0002-2506-5826
Izabela JendrzejewskaInstitute of Chemistry, University of Silesia in Katowice, 40-007 Katowice, Poland.ORCID 0000-0002-6025-5772
Alois CizekDepartment of Infectious Diseases and Microbiology, Faculty of Veterinary Medicine, University of Veterinary Sciences Brno, Palackeho tr. 1946/1, 612 42 Brno, Czech Republic.ORCID 0000-0001-5706-4601
Josef JampilekDepartment of Analytical Chemistry, Faculty of Natural Sciences, Comenius University, Ilkovicova 6, 842 15 Bratislava, Slovakia.

Funding

Czech Ministry of Agriculture RO0518CzeCOS LM2018123FIT CZ.02.1.01/0.0/0.0/15_003/0000495Slovak Research and Development Agency APVV-17-0373SustES CZ.02.1.01/0.0/0.0/16_019/0000797VEGA 1/0116/22
6 · The paper itself

Abstract

A series of thirty-two anilides of 3-(trifluoromethyl)cinnamic acid (series

Indexed as

Methicillin-Resistant Staphylococcus aureusStaphylococcal InfectionsAnti-Bacterial AgentsCinnamatesHumansMicrobial Sensitivity TestsAnti-Bacterial AgentsCinnamatescinnamic acidantimicrobial activitycinnamamidescytotoxicitydocking studylipophilicityMichael acceptorsstructure–activity relationships

Identifiers

PMID36499415
PMCPMC9737391

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.