Evidence map›Paper›PMID 36499380›Full record

ReviewInternational journal of molecular sciences2022

Kaempferol: Antimicrobial Properties, Sources, Clinical, and Traditional Applications.

Argyrios Periferakis, Konstantinos Periferakis, Ioana Anca Badarau, Elena Madalina Petran, Delia Codruta Popa, Ana Caruntu, Raluca Simona Costache, Cristian Scheau, Constantin Caruntu, Daniel Octavian Costache

Abstract readReview
In one paragraph

Review in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 160 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
160citing papers in PubMed, 5 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

160 citing papers in PubMed, 5 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Pooled it
  6. Molecules (Basel, Switzerland) · 2026
    Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Integrated Chemical Profiling and Biological Assessment ofAntibiotics (Basel, Switzerland) · 2026
    Article
  13. Review
  14. Review
  15. Article
  16. Article
  17. Review
  18. Review
  19. International journal of molecular sciences · 2026
    Review
  20. Green Synthesis and Quality-by-Design Optimization ofMolecules (Basel, Switzerland) · 2026
    Article

100 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Argyrios PeriferakisDepartment of Physiology, The "Carol Davila" University of Medicine and Pharmacy, 050474 Bucharest, Romania.ORCID 0000-0002-8319-7464
Konstantinos PeriferakisAkadimia of Ancient Greek and Traditional Chinese Medicine, 16675 Athens, Greece.
Ioana Anca BadarauDepartment of Physiology, The "Carol Davila" University of Medicine and Pharmacy, 050474 Bucharest, Romania.
Elena Madalina PetranDepartment of Biochemistry, The "Carol Davila" University of Medicine and Pharmacy, 050474 Bucharest, Romania.ORCID 0000-0002-6721-9328
Delia Codruta PopaDepartment of Biochemistry, The "Carol Davila" University of Medicine and Pharmacy, 050474 Bucharest, Romania.
Ana CaruntuDepartment of Oral and Maxillofacial Surgery, 'Dr. Carol Davila' Central Military Emergency Hospital, 010825 Bucharest, Romania.ORCID 0000-0003-4200-3069
Raluca Simona CostacheDepartment of Gastroenterology, Gastroenterology and Internal Medicine Clinic, 'Dr. Carol Davila' Central Military Emergency Hospital, 010825 Bucharest, Romania.ORCID 0000-0002-0381-5550
Cristian ScheauDepartment of Physiology, The "Carol Davila" University of Medicine and Pharmacy, 050474 Bucharest, Romania.ORCID 0000-0001-7676-6393
Constantin CaruntuDepartment of Physiology, The "Carol Davila" University of Medicine and Pharmacy, 050474 Bucharest, Romania.ORCID 0000-0003-4530-7965
Daniel Octavian CostacheDepartment of Dermatology, 'Dr. Carol Davila' Central Military Emergency Hospital, 010825 Bucharest, Romania.ORCID 0000-0002-5906-8654

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Flavonoids are a category of plant-derived compounds which exhibit a large number of health-related effects. One of the most well-known and studied flavonoids is kaempferol, which can be found in a wide variety of herbs and plant families. Apart from their anticarcinogenic and anti-inflammatory effects, kaempferol and its associated compounds also exhibit antibacterial, antifungal, and antiprotozoal activities. The development of drugs and treatment schemes based on these compounds is becoming increasingly important in the face of emerging resistance of numerous pathogens as well as complex molecular interactions between various drug therapies. In addition, many of the kaempferol-containing plants are used in traditional systems all over the world for centuries to treat numerous conditions. Due to its variety of sources and associated compounds, some molecular mechanisms of kaempferol antimicrobial activity are well known while others are still under analysis. This paper thoroughly documents the vegetal and food sources of kaempferol as well as the most recent and significant studies regarding its antimicrobial applications.

Indexed as

Anti-Infective AgentsAntiprotozoal AgentsAnti-Bacterial AgentsFlavonoidsKaempferolsAnti-Bacterial AgentsAnti-Infective AgentsAntiprotozoal AgentsFlavonoidskaempferolKaempferolsantibacterialantifungalantiprotozoalherbal medicinekaempferolmolecular mechanisms

Identifiers

PMID36499380
PMCPMC9740324

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.