ArticleInternational journal of molecular sciences2022
Opposite Regulation of Homer Signal at the NMJ Postsynaptic Micro Domain between Slow- and Fast-Twitch Muscles in an Experimentally Induced Autoimmune Myasthenia Gravis (EAMG) Mouse Model.
Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 42% of its field
1 · What the graph read from it
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registry
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literature
Who cites it
1 citing paper in PubMed, 4 citations in OpenAlex.
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what money
Authors and funding
11 authors at 4 institutions in 2 countries.
Martin SchubertInstitute of Integrative Neuroanatomy, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin and Berlin Institute of Health, 10115 Berlin, Germany.ORCID 0000-0003-2063-1849
Andreas PelzDepartment of Experimental Neurology, Charité-Universitätsmedizin Berlin, 10115 Berlin, Germany.ORCID 0000-0002-7111-6970
Gabor TrautmannInstitute of Integrative Neuroanatomy, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin and Berlin Institute of Health, 10115 Berlin, Germany.
Katharina BlockCenter of Space Medicine Berlin, Neuromuscular Signaling and System, 10115 Berlin, Germany.ORCID 0000-0002-2752-5232
Martina GutsmannInstitute of Integrative Neuroanatomy, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin and Berlin Institute of Health, 10115 Berlin, Germany.
Siegfried KohlerDepartment of Experimental Neurology, Charité-Universitätsmedizin Berlin, 10115 Berlin, Germany.
Pompeo VolpeDepartment of Biomedical Sciences, University of Padova, 35122 Padova, Italy.
Dieter BlottnerInstitute of Integrative Neuroanatomy, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin and Berlin Institute of Health, 10115 Berlin, Germany.ORCID 0000-0003-0355-3340
Andreas MeiselDepartment of Experimental Neurology, Charité-Universitätsmedizin Berlin, 10115 Berlin, Germany.ORCID 0000-0001-7233-5342
Michele SalanovaInstitute of Integrative Neuroanatomy, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin and Berlin Institute of Health, 10115 Berlin, Germany.ORCID 0000-0002-7066-3876
Humboldt-Universität zu Berlin · DECharité - Universitätsmedizin Berlin · DENeuroscience Institute · ITUniversity of Padua · IT
Funding
Federal Ministry for Economic Affairs and Climate Action (BMWK) through Deutsches Zentrum fuer Luft- und Raumfahrt (DLR e.V., Bonn-Oberkassel, Germany) 50WB2116
6 · The paper itself
Abstract
Accelerated postsynaptic remodelling and disturbance of neuromuscular transmission are common features of autoimmune neurodegenerative diseases. Homer protein isoform expression, crosslinking activity and neuromuscular subcellular localisation are studied in mouse hind limb muscles of an experimentally induced autoimmune model of Myasthenia Gravis (EAMG) and correlated to motor end plate integrity.
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.
Opposite Regulation of Homer Signal at the NMJ Postsynaptic Micro Domain between Slow- and Fast-Twitch Muscles in an Experimentally Induced Autoimmune Myasthenia Gravis (EAMG) Mouse Model. · full record | OpenQuestion