Evidence map›Paper›PMID 36499357›Full record

ArticleInternational journal of molecular sciences2022

Advanced EPI-X4 Derivatives Covalently Bind Human Serum Albumin Resulting in Prolonged Plasma Stability.

Armando Rodríguez-Alfonso, Astrid Heck, Yasser Bruno Ruiz-Blanco, Andrea Gilg, Ludger Ständker, Seah Ling Kuan, Tanja Weil, Elsa Sanchez-Garcia, Sebastian Wiese, Jan Münch and 1 more

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Regulatory Guidelines for the Analysis of Therapeutic Peptides and Proteins.Journal of peptide science : an official publication of the European Peptide Society · 2025
    Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Lipidation of a bioactive cyclotide-based CXCR4 antagonist greatly improves its pharmacokinetic profile in vivo.Journal of controlled release : official journal of the Controlled Release Society · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Armando Rodríguez-AlfonsoCore Facility Functional Peptidomics, Ulm University Medical Center, 89081 Ulm, Germany.ORCID 0000-0001-5921-3770
Astrid HeckMax Planck Institute for Polymer Research, 55128 Mainz, Germany.
Yasser Bruno Ruiz-BlancoCenter of Medical Biotechnology, University of Duisburg-Essen, 47057 Duisburg, Germany.
Andrea GilgInstitute of Molecular Virology, Ulm University Medical Center, 89081 Ulm, Germany.
Ludger StändkerCore Facility Functional Peptidomics, Ulm University Medical Center, 89081 Ulm, Germany.ORCID 0000-0002-8436-4260
Seah Ling KuanMax Planck Institute for Polymer Research, 55128 Mainz, Germany.
Tanja WeilMax Planck Institute for Polymer Research, 55128 Mainz, Germany.ORCID 0000-0002-5906-7205
Elsa Sanchez-GarciaCenter of Medical Biotechnology, University of Duisburg-Essen, 47057 Duisburg, Germany.
Sebastian WieseCore Unit Mass Spectrometry and Proteomics, Ulm University Medical Center, 89081 Ulm, Germany.
Jan MünchCore Facility Functional Peptidomics, Ulm University Medical Center, 89081 Ulm, Germany.ORCID 0000-0001-7316-7141
Mirja HarmsInstitute of Molecular Virology, Ulm University Medical Center, 89081 Ulm, Germany.ORCID 0000-0002-5460-5166
Universität Ulm · DEMax Planck Institute for Polymer Research · DEUniversity of Duisburg-Essen · DE

Funding

Baden-Württemberg Stiftung BWST_WSF-025Deutsche Forschungsgemeinschaft 3115/11-1Deutsche Forschungsgemeinschaft 436586093Deutsche Forschungsgemeinschaft CRC1279Deutsche Forschungsgemeinschaft EXC 2033 - 390677874 614 - RESOLVDeutsche Forschungsgemeinschaft MU 3115/8-1University of Ulm L.SBN.0209
6 · The paper itself

Abstract

Advanced derivatives of the

Indexed as

Receptors, CXCR4Serum Albumin, HumanAnimalsHalf-LifeHumansPeptidesSerum AlbuminPeptidesReceptors, CXCR4Serum AlbuminSerum Albumin, Humanalbumin carrierCXCR4 antagonistEPI-X4peptide stability

Identifiers

PMID36499357
PMCPMC9735595
OpenAlexW4310375418

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.