Evidence map›Paper›PMID 36499306›Full record

ArticleInternational journal of molecular sciences2022

FOXG1 Contributes Adult Hippocampal Neurogenesis in Mice.

Jia Wang, Hong-Ru Zhai, Si-Fei Ma, Hou-Zhen Shi, Wei-Jun Zhang, Qi Yun, Wen-Jun Liu, Zi-Zhong Liu, Wei-Ning Zhang

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 19 citations in OpenAlex.

  1. Pooled it
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  5. Coupling of stemness maintenance with cell cycle control in stem cells.Frontiers in cell and developmental biology · 2025
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Jia WangDepartment of Neurology, The Fourth Affiliated Hospital of Jiangsu University, Zhenjiang 212001, China.ORCID 0000-0002-9544-9366
Hong-Ru ZhaiDepartment of Laboratory Medicine, School of Medicine, Jiangsu University, Zhenjiang 212013, China.
Si-Fei MaDepartment of Laboratory Medicine, School of Medicine, Jiangsu University, Zhenjiang 212013, China.
Hou-Zhen ShiDepartment of Laboratory Medicine, School of Medicine, Jiangsu University, Zhenjiang 212013, China.
Wei-Jun ZhangDepartment of Laboratory Medicine, School of Medicine, Jiangsu University, Zhenjiang 212013, China.
Qi YunDepartment of Laboratory Medicine, School of Medicine, Jiangsu University, Zhenjiang 212013, China.
Wen-Jun LiuDepartment of Laboratory Medicine, School of Medicine, Jiangsu University, Zhenjiang 212013, China.
Zi-Zhong LiuDepartment of Neurology, The Fourth Affiliated Hospital of Jiangsu University, Zhenjiang 212001, China.
Wei-Ning ZhangDepartment of Laboratory Medicine, School of Medicine, Jiangsu University, Zhenjiang 212013, China.
Jiangsu University · CN

Funding

Clinic Development Fund of Jiangsu Province BE2022782Science and Technology Planning Social Development Project of Zhenjiang City SH2022059The International Cooperation Projects of Zhenjiang City GJ2021010
6 · The paper itself

Abstract

Strategies to enhance hippocampal precursor cells efficiently differentiate into neurons could be crucial for structural repair after neurodegenerative damage. FOXG1 has been shown to play an important role in pattern formation, cell proliferation, and cell specification during embryonic and early postnatal neurogenesis. Thus far, the role of FOXG1 in adult hippocampal neurogenesis is largely unknown. Utilizing CAG-loxp-stop-loxp-Foxg1-IRES-EGFP (

Indexed as

Neural Stem CellsNeurogenesisAnimalsCell ProliferationForkhead Transcription FactorsHippocampusMiceMice, Inbred C57BLNerve Tissue ProteinsNeuronsForkhead Transcription FactorsFoxg1 protein, mouseNerve Tissue ProteinsAlzheimer’s diseasecell cycleFOXG1hippocampusneural stem cell

Identifiers

PMID36499306
PMCPMC9735854
OpenAlexW4310999184

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.