Evidence map›Paper›PMID 36499281›Full record

ArticleInternational journal of molecular sciences2022

N-Linked Glycosylation in Chinese Hamster Ovary Cells Is Critical for Insulin-like Growth Factor 1 Signaling.

Rupashree Salvi, Chandan Kumar, Krupanshi Brahmbhatt, Rambhadur Subedi, Susan Idicula-Thomas, Taruna Madan, Barnali Biswas

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.3field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Rupashree SalviDepartment of Innate Immunity, ICMR-National Institute for Research in Reproductive and Child Health, Mumbai 400012, India.
Chandan KumarBiomedical Informatics Centre, ICMR-National Institute for Research in Reproductive and Child Health, Mumbai 400012, India.
Krupanshi BrahmbhattDepartment of Innate Immunity, ICMR-National Institute for Research in Reproductive and Child Health, Mumbai 400012, India.
Rambhadur SubediDepartment of Innate Immunity, ICMR-National Institute for Research in Reproductive and Child Health, Mumbai 400012, India.
Susan Idicula-ThomasBiomedical Informatics Centre, ICMR-National Institute for Research in Reproductive and Child Health, Mumbai 400012, India.
Taruna MadanDepartment of Innate Immunity, ICMR-National Institute for Research in Reproductive and Child Health, Mumbai 400012, India.
Barnali BiswasDepartment of Innate Immunity, ICMR-National Institute for Research in Reproductive and Child Health, Mumbai 400012, India.
National Institute for Research in Reproductive Health · IN

Funding

Department of Biotechnology BT/PR30734/med/97/435/2018Department of Biotechnology BT/PR40165/BTIS/137/12/2021Department of Science and Technology DST/INSPIRE/04/2017/001636]
6 · The paper itself

Abstract

Cell surface proteins carrying N-glycans play important roles in inter- and intracellular processes including cell adhesion, development, and cellular recognition. Dysregulation of the glycosylation machinery has been implicated in various diseases, and investigation of global differential cell surface proteome effects due to the loss of N-glycosylation will provide comprehensive insights into their pathogenesis. Cell surface proteins isolated from Parent Pro

Indexed as

Insulin-Like Growth Factor IAnimalsCHO CellsCricetinaeCricetulusGlycosylationGTPase-Activating ProteinsIntegrinsPhosphorylationReceptor, IGF Type 1GTPase-Activating ProteinsInsulin-Like Growth Factor IIntegrinsReceptor, IGF Type 1insulin-like growth factor 1 receptorintegrinsMAP kinases (MAPKs)N-glycosylationOrbitrap Mass Spectrometry (MS)protein phosphorylationRas GTPase activating Protein (IQGAP1)receptor tyrosine kinase

Identifiers

PMID36499281
PMCPMC9735751
OpenAlexW4310995833

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.