Evidence map›Paper›PMID 36499240›Full record

ReviewInternational journal of molecular sciences2022

Alcohol Withdrawal and the Associated Mood Disorders-A Review.

Helena Hui Lin Ngui, Audrey Siew Foong Kow, Sally Lai, Chau Ling Tham, Yu-Cheng Ho, Ming Tatt Lee

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
2.9field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 26 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Biochemistry and biophysics reports · 2026
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Review
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Helena Hui Lin NguiFaculty of Pharmaceutical Sciences, UCSI University, Kuala Lumpur 56000, Malaysia.
Audrey Siew Foong KowFaculty of Pharmaceutical Sciences, UCSI University, Kuala Lumpur 56000, Malaysia.
Sally LaiFaculty of Pharmaceutical Sciences, UCSI University, Kuala Lumpur 56000, Malaysia.
Chau Ling ThamDepartment of Biomedical Sciences, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, Serdang 43400, Malaysia.ORCID 0000-0002-9734-0372
Yu-Cheng HoSchool of Medicine, College of Medicine, I-Shou University, Kaohsiung City 82445, Taiwan.
Ming Tatt LeeFaculty of Pharmaceutical Sciences, UCSI University, Kuala Lumpur 56000, Malaysia.ORCID 0000-0003-3957-2439
UCSI University · MYI-Shou University · TWUniversiti Putra Malaysia · MY

Funding

Ministry of Higher Education FRGS/1/2021/WAB13/UCSI/02/1 and FRGS/1/2018/SKK10/UPM/02/2)UCSI University REIG-FPS-2020/065 and REIG-FPS-2022/006
6 · The paper itself

Abstract

Recreational use of alcohol is a social norm in many communities worldwide. Alcohol use in moderation brings pleasure and may protect the cardiovascular system. However, excessive alcohol consumption or alcohol abuse are detrimental to one's health. Three million deaths due to excessive alcohol consumption were reported by the World Health Organization. Emerging evidence also revealed the danger of moderate consumption, which includes the increased risk to cancer. Alcohol abuse and periods of withdrawal have been linked to depression and anxiety. Here, we present the effects of alcohol consumption (acute and chronic) on important brain structures-the frontal lobe, the temporal lobe, the limbic system, and the cerebellum. Apart from this, we also present the link between alcohol abuse and withdrawal and mood disorders in this review, thus drawing a link to oxidative stress. In addition, we also discuss the positive impacts of some pharmacotherapies used. Due to the ever-rising demands of life, the cycle between alcohol abuse, withdrawal, and mood disorders may be a never-ending cycle of destruction. Hence, through this review, we hope that we can emphasise the importance and urgency of managing this issue with the appropriate approaches.

Indexed as

AlcoholismSubstance Withdrawal SyndromeAlcohol DrinkingAnxiety DisordersHumansMood Disordersalcoholanxietydepressionoxidative stresssubstance abusewithdrawal

Identifiers

PMID36499240
PMCPMC9738481
OpenAlexW4310182098

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.