Evidence map›Paper›PMID 36499233›Full record

ArticleInternational journal of molecular sciences2022

Two Epitope Regions Revealed in the Complex of IL-17A and Anti-IL-17A V

Olga Kostareva, Arina Svoeglazova, Ilya Kolyadenko, Alexey Nikulin, Stanislav Evdokimov, Uliana Dzhus, Azat Gabdulkhakov, Svetlana Tishchenko

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.5field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

  1. Engineering of Surface Display Systems inBiotech (Basel (Switzerland)) · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Olga KostarevaInstitute of Protein Research, Russian Academy of Sciences, Institutskaya, 4, 142290 Pushchino, Russia.ORCID 0000-0002-9937-8841
Arina SvoeglazovaInstitute of Protein Research, Russian Academy of Sciences, Institutskaya, 4, 142290 Pushchino, Russia.
Ilya KolyadenkoInstitute of Protein Research, Russian Academy of Sciences, Institutskaya, 4, 142290 Pushchino, Russia.
Alexey NikulinInstitute of Protein Research, Russian Academy of Sciences, Institutskaya, 4, 142290 Pushchino, Russia.
Stanislav EvdokimovCJSC Biocad, ul.Svyazi., 34-A, sett. Strelna, 198515 Saint-Petersburg, Russia.
Uliana DzhusInstitute of Protein Research, Russian Academy of Sciences, Institutskaya, 4, 142290 Pushchino, Russia.
Azat GabdulkhakovInstitute of Protein Research, Russian Academy of Sciences, Institutskaya, 4, 142290 Pushchino, Russia.ORCID 0000-0003-1016-5936
Svetlana TishchenkoInstitute of Protein Research, Russian Academy of Sciences, Institutskaya, 4, 142290 Pushchino, Russia.ORCID 0000-0003-4056-310X
Institute of Protein Research · RUBIOCAD (Russia) · RU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Interleukin-17 (IL-17) is a cytokine produced by the Th17 cells. It is involved in chronic inflammation in patients with autoimmune diseases, such as rheumatoid arthritis, systemic lupus erythematosus, multiple sclerosis, and psoriasis. The antibodies targeting IL-17 and/or IL-17R are therapy tools for these diseases. Netakimab is an IL-17A-specific antibody containing a

Indexed as

Autoimmune DiseasesPsoriasisEpitopesHumansInterleukin-17Th17 CellsEpitopesInterleukin-17crystal structureinterleukin 17A in complex with VHH domainnetakimab

Identifiers

PMID36499233
PMCPMC9738047
OpenAlexW4310182081

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.