Evidence map›Paper›PMID 36499164›Full record

ArticleInternational journal of molecular sciences2022

SRSF3 and HNRNPH1 Regulate Radiation-Induced Alternative Splicing of Protein Arginine Methyltransferase 5 in Hepatocellular Carcinoma.

Chaowei Wen, Zhujun Tian, Lan Li, Tongke Chen, Huajian Chen, Jichen Dai, Zhenzhen Liang, Shumei Ma, Xiaodong Liu

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 16 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Review
  5. Tumor-promoting effect and tumor immunity of SRSFs.Frontiers in cell and developmental biology · 2025
    Review
  6. Article
  7. Review
  8. Review
  9. Article
  10. Review
  11. Article
  12. Protein arginine methylation in transcription and epigenetic regulation.Frontiers in epigenetics and epigenomics · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Chaowei WenSchool of Public Health and Management, Wenzhou Medical University, Wenzhou 325035, China.ORCID 0000-0003-2877-8810
Zhujun TianSchool of Public Health and Management, Wenzhou Medical University, Wenzhou 325035, China.
Lan LiSchool of Public Health and Management, Wenzhou Medical University, Wenzhou 325035, China.
Tongke ChenLaboratory Animal Center, Wenzhou Medical University, Wenzhou 325035, China.
Huajian ChenSchool of Public Health and Management, Wenzhou Medical University, Wenzhou 325035, China.
Jichen DaiSchool of the 2nd Clinical Medical Sciences, Wenzhou Medical University, Wenzhou 325035, China.
Zhenzhen LiangSchool of Public Health and Management, Wenzhou Medical University, Wenzhou 325035, China.
Shumei MaSchool of Public Health and Management, Wenzhou Medical University, Wenzhou 325035, China.
Xiaodong LiuSchool of Public Health and Management, Wenzhou Medical University, Wenzhou 325035, China.
Wenzhou Medical University · CNJilin University · CN

Funding

National Natural Science Foundation of China 81773363National Natural Science Foundation of China 81972969Zhejiang Provincial Medical and Health Science and Technology Project of China 2018KY508
6 · The paper itself

Abstract

Protein arginine methyltransferase 5 (PRMT5) is an epigenetic regulator which has been proven to be a potential target for cancer therapy. We observed that

Indexed as

Carcinoma, HepatocellularLiver NeoplasmsAlternative SplicingCell Line, TumorHeterogeneous-Nuclear RibonucleoproteinsHumansProtein-Arginine N-MethyltransferasesRNA PrecursorsSerine-Arginine Splicing FactorsHeterogeneous-Nuclear RibonucleoproteinsPRMT5 protein, humanProtein-Arginine N-MethyltransferasesRNA PrecursorsSerine-Arginine Splicing FactorsSRSF3 protein, humanalternative splicingHCCHNRNPH1ionizing radiationprotein arginine methyltransferase 5SRSF3

Identifiers

PMID36499164
PMCPMC9738276
OpenAlexW4311002989

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.