Evidence map›Paper›PMID 36499160›Full record

ArticleInternational journal of molecular sciences2022

ROS-Induced DNA-Damage and Autophagy in Oral Squamous Cell Carcinoma by

Violeta Popovici, Adina Magdalena Musuc, Elena Matei, Oana Karampelas, Emma Adriana Ozon, Georgeta Camelia Cozaru, Verginica Schröder, Laura Bucur, Ludmila Aricov, Mihai Anastasescu and 4 more

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
5.6field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 15 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 3 institutions in 1 country.

Violeta PopoviciDepartment of Microbiology and Immunology, Faculty of Dental Medicine, Ovidius University of Constanta, 7 Ilarie Voronca Street, 900684 Constanta, Romania.ORCID 0000-0001-9696-5728
Adina Magdalena Musuc"Ilie Murgulescu" Institute of Physical Chemistry, Romanian Academy, 202 Spl. Independentei, 060021 Bucharest, Romania.ORCID 0000-0002-6935-8065
Elena MateiCenter for Research and Development of the Morphological and Genetic Studies of Malignant Pathology, Ovidius University of Constanta, CEDMOG, 145 Tomis Blvd., 900591 Constanta, Romania.ORCID 0000-0002-8554-7739
Oana KarampelasDepartment of Pharmaceutical Technology and Biopharmacy, Faculty of Pharmacy, Carol Davila University of Medicine and Pharmacy, 6 Traian Vuia Street, 020956 Bucharest, Romania.
Emma Adriana OzonDepartment of Pharmaceutical Technology and Biopharmacy, Faculty of Pharmacy, Carol Davila University of Medicine and Pharmacy, 6 Traian Vuia Street, 020956 Bucharest, Romania.
Georgeta Camelia CozaruCenter for Research and Development of the Morphological and Genetic Studies of Malignant Pathology, Ovidius University of Constanta, CEDMOG, 145 Tomis Blvd., 900591 Constanta, Romania.
Verginica SchröderDepartment of Cellular and Molecular Biology, Faculty of Pharmacy, Ovidius University of Constanta, 6 Capitan Al. Serbanescu Street, 900001 Constanta, Romania.ORCID 0000-0001-8876-1901
Laura BucurDepartment of Pharmacognosy, Faculty of Pharmacy, Ovidius University of Constanta, 6 Capitan Al. Serbanescu Street, 900001 Constanta, Romania.
Ludmila Aricov"Ilie Murgulescu" Institute of Physical Chemistry, Romanian Academy, 202 Spl. Independentei, 060021 Bucharest, Romania.ORCID 0000-0002-6472-6172
Mihai Anastasescu"Ilie Murgulescu" Institute of Physical Chemistry, Romanian Academy, 202 Spl. Independentei, 060021 Bucharest, Romania.ORCID 0000-0002-4865-2652
Mariana AșchieCenter for Research and Development of the Morphological and Genetic Studies of Malignant Pathology, Ovidius University of Constanta, CEDMOG, 145 Tomis Blvd., 900591 Constanta, Romania.
Victoria BadeaDepartment of Microbiology and Immunology, Faculty of Dental Medicine, Ovidius University of Constanta, 7 Ilarie Voronca Street, 900684 Constanta, Romania.
Dumitru LupuliasaDepartment of Pharmaceutical Technology and Biopharmacy, Faculty of Pharmacy, Carol Davila University of Medicine and Pharmacy, 6 Traian Vuia Street, 020956 Bucharest, Romania.
Cerasela Elena GîrdDepartment of Pharmacognosy, Phytochemistry, and Phytotherapy, Faculty of Pharmacy, Carol Davila University of Medicine and Pharmacy, 6 Traian Vuia Street, 020956 Bucharest, Romania.ORCID 0000-0003-4372-4335
Ovidius University · ROCarol Davila University of Medicine and Pharmacy · RORomanian Academy · RO

Funding

The APC was supported by UMF Carol Davila Bucharest, Romania. This project was supported by the project ANTREPRENORDOC, in the framework of the Human Resources Development Operational Programme 2014-2020, financed from the European Social Fund Contract number: 36355/23.05.2019 HRD OP/380/6/13-SMIS Code: 123847.
6 · The paper itself

Abstract

Oxidative stress is associated with aging, cancers, and numerous metabolic and chronic disorders, and phenolic compounds are well known for their health-promoting role due to their free-radical scavenging activity. These phytochemicals could also exhibit pro-oxidant effects. Due to its bioactive phenolic secondary metabolites,

Indexed as

Carcinoma, Squamous CellHead and Neck NeoplasmsMouth NeoplasmsUsneaApoptosisAutophagyCell Line, TumorDNADNA DamageHumansPhenolsPlant ExtractsRapeseed OilReactive Oxygen SpeciesSquamous Cell Carcinoma of Head and NeckDNAPhenolsPlant ExtractsRapeseed OilReactive Oxygen Speciesblood cell culturescanola oilCLS-354 OSCC cell linecytotoxicityphenolic secondary metabolitesreactive oxygen speciesUsnea barbata (L.) Weber ex F.H. Wigg

Identifiers

PMID36499160
PMCPMC9738295
OpenAlexW4310479471

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.