Evidence map›Paper›PMID 36499140›Full record

ReviewInternational journal of molecular sciences2022

Chemistry towards Biology-Instruct: Snapshot.

Miloš Hricovíni, Raymond J Owens, Andrzej Bak, Violetta Kozik, Witold Musiał, Roberta Pierattelli, Magdaléna Májeková, Yoel Rodríguez, Robert Musioł, Aneta Slodek and 6 more

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Chemistry towards Biology.International journal of molecular sciences · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Miloš HricovíniInstitute of Chemistry, Slovak Academy of Sciences, Dúbravská cesta 9, 845 38 Bratislava, Slovakia.
Raymond J OwensStructural Biology, The Rosalind Franklin Institute, Harwell Science Campus, UK, University of Oxford, Oxford OX11 0QS, UK.ORCID 0000-0002-3705-2993
Andrzej BakInstitute of Chemistry, University of Silesia, Szkolna 9, 40 007 Katowice, Poland.ORCID 0000-0002-9842-1289
Violetta KozikInstitute of Chemistry, University of Silesia, Szkolna 9, 40 007 Katowice, Poland.
Witold MusiałDepartment of Physical Chemistry and Biophysics, Pharmaceutical Faculty, Wroclaw Medical University, Borowska 211A, 50 556 Wrocław, Poland.
Roberta PierattelliMagnetic Resonance Center and Department of Chemistry "Ugo Schiff", University of Florence, 50019 Sesto Fiorentino, Italy.ORCID 0000-0001-7755-0885
Magdaléna MájekováCenter of Experimental Medicine SAS and Department of Biochemical Pharmacology, Institute of Experimental Pharmacology and Toxicology, Slovak Academy of Sciences, Dubravska cesta 9, 841 04 Bratislava, Slovakia.ORCID 0000-0001-8633-3276
Yoel RodríguezDepartment of Natural Sciences, Eugenio María de Hostos Community College, City University of New York, 500 Grand Concourse, Bronx, NY 10451, USA.ORCID 0000-0002-7334-7828
Robert MusiołInstitute of Chemistry, University of Silesia, Szkolna 9, 40 007 Katowice, Poland.ORCID 0000-0002-6219-7369
Aneta SlodekInstitute of Chemistry, University of Silesia, Szkolna 9, 40 007 Katowice, Poland.ORCID 0000-0003-2600-6518
Pavel ŠtarhaDepartment of Inorganic Chemistry, Faculty of Science, Palacký University Olomouc, 17. listopadu 1192/12, 771 46 Olomouc, Czech Republic.ORCID 0000-0003-0422-045X
Karina PiętakDepartment of Materials Science, Faculty of Materials Engineering and Physics, Cracow University of Technology, 37 Jana Pawła II Av., 31 864 Krakow, Poland.ORCID 0000-0001-7970-3478
Dagmara SłotaDepartment of Materials Science, Faculty of Materials Engineering and Physics, Cracow University of Technology, 37 Jana Pawła II Av., 31 864 Krakow, Poland.
Wioletta FlorkiewiczDepartment of Materials Science, Faculty of Materials Engineering and Physics, Cracow University of Technology, 37 Jana Pawła II Av., 31 864 Krakow, Poland.ORCID 0000-0002-9392-4362
Agnieszka Sobczak-KupiecDepartment of Materials Science, Faculty of Materials Engineering and Physics, Cracow University of Technology, 37 Jana Pawła II Av., 31 864 Krakow, Poland.ORCID 0000-0003-0005-6146
Josef JampílekDepartment of Analytical Chemistry, Faculty of Natural Sciences, Comenius University, Ilkovičova 6, 842 15 Bratislava, Slovakia.ORCID 0000-0003-2003-9052

Funding

Medical Research Council MR/V03958X/1Wellcome Trust 100209/Z/12/Z, 223733/Z/21
6 · The paper itself

Abstract

The knowledge of interactions between different molecules is undoubtedly the driving force of all contemporary biomedical and biological sciences. Chemical biology/biological chemistry has become an important multidisciplinary bridge connecting the perspectives of chemistry and biology to the study of small molecules/peptidomimetics and their interactions in biological systems. Advances in structural biology research, in particular linking atomic structure to molecular properties and cellular context, are essential for the sophisticated design of new medicines that exhibit a high degree of druggability and very importantly, druglikeness. The authors of this contribution are outstanding scientists in the field who provided a brief overview of their work, which is arranged from in silico investigation through the characterization of interactions of compounds with biomolecules to bioactive materials.

Indexed as

Molecular Biologybiological chemistrybiomaterialsbiomoleculeschemical biologymolecular interactionsnatural compoundsproteins and nucleic acidsstructure and dynamicstargetingvirtual screening

Identifiers

PMID36499140
PMCPMC9739621

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.