Evidence map›Paper›PMID 36499099›Full record

ArticleInternational journal of molecular sciences2022

Cancer Stem Cell Formation Induced and Regulated by Extracellular ATP and Stanniocalcin-1 in Human Lung Cancer Cells and Tumors.

Jingwen Song, Yanrong Qian, Maria Evers, Corinne M Nielsen, Xiaozhuo Chen

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Extracellular Adenosine in Gastric Cancer: The Role of GCSCs.International journal of molecular sciences · 2025
    Article
  3. Article
  4. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Jingwen SongDepartment of Biological Science, Ohio University, Athens, OH 45701, USA.
Yanrong QianThe Molecular and Cellular Biology Program, Ohio University, Athens, OH 45701, USA.ORCID 0000-0002-3950-2759
Maria EversEdison Biotechnology Institute, Ohio University, Athens, OH 45701, USA.
Corinne M NielsenDepartment of Biological Science, Ohio University, Athens, OH 45701, USA.ORCID 0000-0002-8500-6035
Xiaozhuo ChenDepartment of Biological Science, Ohio University, Athens, OH 45701, USA.ORCID 0000-0001-9635-4572
Biotechnology Institute · USOhio University · US

Funding

Extracellular ATP in cancer: mechanism study of ATP internalization and ATP-induced drug resistance in cancer cells and tumorsR15CA242177 · NCI · OHIO UNIVERSITY ATHENS · PI CHEN, XIAOZHUO · 2019 to 2019
$450k
NIH HHS R15 CA242177-01
6 · The paper itself

Abstract

Cancer stem cells (CSCs) are closely associated with metastasis and epithelial mesenchymal transition (EMT). We previously reported that extracellular ATP (eATP) induces and regulates EMT in cancer cells. We recently found that the gene stanniocalcin 1 (

Indexed as

Lung NeoplasmsA549 CellsAdenosine TriphosphateCell Line, TumorEpithelial-Mesenchymal TransitionGene Expression Regulation, NeoplasticHumansNeoplastic Stem CellsAdenosine Triphosphateanimal studycancer metabolismCRISPR Cas9 KnockouteATPEMTmetabolic analysismetastasisprotein markersRNA sequencingSTC1

Identifiers

PMID36499099
PMCPMC9740946
OpenAlexW4310244892

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.