Evidence map›Paper›PMID 36499079›Full record

ReviewInternational journal of molecular sciences2022

Electrolyzed-Reduced Water: Review I. Molecular Hydrogen Is the Exclusive Agent Responsible for the Therapeutic Effects.

Tyler W LeBaron, Randy Sharpe, Kinji Ohno

Abstract readReview
In one paragraph

Review in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Hydrogen Water: Extra Healthy or a Hoax?-A Systematic Review.International journal of molecular sciences · 2024
    Pooled it
  2. Review
  3. Article
  4. Article
  5. Article
  6. Review
  7. Progress in the Application of Molecular Hydrogen in Medical Skin Cosmetology.Clinical, cosmetic and investigational dermatology · 2025
    Review
  8. You Are What You Drink: A Project Summary of Water Quality in Tuskegee, Alabama.Journal of healthcare, science and the humanities · 2025
    Article
  9. Review
  10. Article
  11. Review
  12. Review
  13. Novel COScientific reports · 2023
    Article
  14. Review
  15. Review
  16. Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Tyler W LeBaronCentre of Experimental Medicine, Institute for Heart Research, Slovak Academy of Sciences, 841 04 Bratislava, Slovakia.
Randy SharpeH2 Analytics, Henderson, NV 89052, USA.
Kinji OhnoDivision of Neurogenetics, Center for Neurological Diseases and Cancer, Nagoya University Graduate School of Medicine, Nagoya 466-855, Japan.ORCID 0000-0002-1529-2750

Funding

Japan Agency for Medical Research and Development JP21gm1010002
6 · The paper itself

Abstract

Numerous benefits have been attributed to alkaline-electrolyzed-reduced water (ERW). Sometimes these claims are associated with easily debunked concepts. The observed benefits have been conjectured to be due to the intrinsic properties of ERW (e.g., negative oxidation-reduction potential (ORP), alkaline pH, H

Indexed as

ElectrolysisWaterHydrogenHydrogen-Ion ConcentrationHydrogenWateralkali ion wateralkaline-ionized wateralkaline-reduced wateralkaline waterelectrolyzed–reduced waterfunctional waterhydrogen waterionized water

Identifiers

PMID36499079
PMCPMC9738607

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.