Evidence map›Paper›PMID 36499025›Full record

ArticleInternational journal of molecular sciences2022

Chlamydial Infection-Dependent Synthesis of Sphingomyelin as a Novel Anti-Chlamydial Target of Ceramide Mimetic Compounds.

Keigo Kumagai, Shota Sakai, Masaharu Ueno, Michiyo Kataoka, Shu Kobayashi, Kentaro Hanada

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.7field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Keigo KumagaiDepartment of Biochemistry and Cell Biology, National Institute of Infectious Diseases, 1-23-1 Toyama, Shinjuku-ku, Tokyo 162-8640, Japan.
Shota SakaiDepartment of Biochemistry and Cell Biology, National Institute of Infectious Diseases, 1-23-1 Toyama, Shinjuku-ku, Tokyo 162-8640, Japan.
Masaharu UenoDepartment of Natural Science, Graduate School of Advanced Technology and Science, Tokushima University, 2-1 Minami-jousanjima, Tokushima 770-8506, Japan.ORCID 0000-0001-5253-0968
Michiyo KataokaDepartment of Pathology, National Institute of Infectious Diseases, 1-23-1 Toyama, Shinjuku-ku, Tokyo 162-8640, Japan.
Shu KobayashiDepartment of Chemistry, School of Science, University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 110-0033, Japan.
Kentaro HanadaDepartment of Biochemistry and Cell Biology, National Institute of Infectious Diseases, 1-23-1 Toyama, Shinjuku-ku, Tokyo 162-8640, Japan.
National Institute of Infectious Diseases · JPTokushima University · JPTokyo University of Science · JP

Funding

Japan Agency for Medical Research and Development JP20gm0910005j0006Japan Society for the Promotion of Science JP18K06649Japan Society for the Promotion of Science JP22K06626Ministry of Education, Culture, Sports, Science and Technology JP17H06417
6 · The paper itself

Abstract

The obligate intracellular bacterium

Indexed as

CeramidesSphingomyelinsAmidesChlamydia trachomatisHeLa CellsHumansPhosphorylcholineProtein Serine-Threonine KinasesAmidesCeramidesN-(3-hydroxy-1-hydroxymethyl-3-phenylpropyl)dodecanamidePhosphorylcholineProtein Serine-Threonine KinasesSphingomyelinsantibioticsbacterial metabolismceramideCERTChlamydia trachomatisinfectious diseaseinhibitorsphingolipidsphingomyelin synthasestereoselectivity

Identifiers

PMID36499025
PMCPMC9735676
OpenAlexW4310249369

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.