ArticleInternational journal of molecular sciences2022
Hepatic Oleate Regulates Insulin-like Growth Factor-Binding Protein 1 Partially through the mTORC1-FGF21 Axis during High-Carbohydrate Feeding.
Lucas M O'Neill, Yar Xin Phang, Zhaojin Liu, Sarah A Lewis, Ahmed Aljohani, Ayren McGahee, Gina Wade, Mugagga Kalyesubula, Judith Simcox, James M Ntambi
Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 47% of its field
1 · What the graph read from it
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registry
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literature
Who cites it
2 citing papers in PubMed, 3 citations in OpenAlex.
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what money
Authors and funding
10 authors at 2 institutions in 2 countries.
Lucas M O'NeillDepartment of Biochemistry, University of Wisconsin-Madison, 433 Babcock Drive, Madison, WI 53706, USA.
Yar Xin PhangDepartment of Biochemistry, University of Wisconsin-Madison, 433 Babcock Drive, Madison, WI 53706, USA.
Zhaojin LiuDepartment of Biochemistry, University of Wisconsin-Madison, 433 Babcock Drive, Madison, WI 53706, USA.ORCID 0000-0002-9574-5974
Sarah A LewisDepartment of Biochemistry, University of Wisconsin-Madison, 433 Babcock Drive, Madison, WI 53706, USA.
Ahmed AljohaniCollege of Science and Health Professions, King Saud Bin Abdulaziz University for Health Sciences, Riyadh 11564, Saudi Arabia.
Ayren McGaheeDepartment of Biochemistry, University of Wisconsin-Madison, 433 Babcock Drive, Madison, WI 53706, USA.
Gina WadeDepartment of Biochemistry, University of Wisconsin-Madison, 433 Babcock Drive, Madison, WI 53706, USA.
Mugagga KalyesubulaDepartment of Biochemistry, University of Wisconsin-Madison, 433 Babcock Drive, Madison, WI 53706, USA.
Judith SimcoxDepartment of Biochemistry, University of Wisconsin-Madison, 433 Babcock Drive, Madison, WI 53706, USA.ORCID 0000-0001-7350-6342
James M NtambiDepartment of Biochemistry, University of Wisconsin-Madison, 433 Babcock Drive, Madison, WI 53706, USA.ORCID 0000-0001-9784-9550
University of Wisconsin–Madison · USKing Saud bin Abdulaziz University for Health Sciences · SA
Funding
GRADUATE TRAINING IN MOLECULAR BIOSCIENCEST32GM007215 · NIGMS · UNIVERSITY OF WISCONSIN-MADISON · PI HULL, CHRISTINA M · 1985 to 2018
$22.5M
Discovery and characterization of a novel acylcarnitine transporter in brown adipocytesR01DK133479 · NIDDK · UNIVERSITY OF WISCONSIN-MADISON · PI Judith Anne Simcox · 2022 to 2026
$1.5M
Role of Liver Stearoyl-CoA Desaturase-1 in the Regulation of MetabolismR01DK118093 · NIDDK · UNIVERSITY OF WISCONSIN-MADISON · PI NTAMBI, JAMES M. · 2018 to 2020
Stearoyl-CoA desaturase-1 (SCD1) catalyzes the rate-liming step of monounsaturated fatty acid biosynthesis and is a key regulator of systemic glucose metabolism. Mice harboring either a global (GKO) or liver-specific deletion (LKO) of
Indexed as
Insulin-Like Growth Factor Binding Protein 1Mechanistic Target of Rapamycin Complex 1Oleic AcidStearoyl-CoA DesaturaseAnimalsDietary CarbohydratesFibroblast Growth FactorsInsulinLiverMiceObesityDietary Carbohydratesfibroblast growth factor 21Fibroblast Growth FactorsInsulinInsulin-Like Growth Factor Binding Protein 1Mechanistic Target of Rapamycin Complex 1Oleic AcidScd1 protein, mouseStearoyl-CoA Desaturasefibroblast growth factor 21insulin-like growth factor-binding protein 1mechanistic target of rapamycinoleic acidstearic acidstearoyl-CoA desaturase-1
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.
Hepatic Oleate Regulates Insulin-like Growth Factor-Binding Protein 1 Partially through the mTORC1-FGF21 Axis during High-Carbohydrate Feeding. · full record | OpenQuestion