Evidence map›Paper›PMID 36498955›Full record

ReviewInternational journal of molecular sciences2022

Therapeutic Potential of Plant Oxylipins.

Tatyana Savchenko, Evgeny Degtyaryov, Yaroslav Radzyukevich, Vlada Buryak

Abstract readReview
In one paragraph

Review in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Review
  6. The Known Unknowns: An Enigmatic Pathway of CCurrent issues in molecular biology · 2025
    Review
  7. Review
  8. Review
  9. Review
  10. Article
  11. Review
  12. RepurposingLife (Basel, Switzerland) · 2024
    Article
  13. Article
  14. Epoxyalcohol Synthase Branch of Lipoxygenase Cascade.Current issues in molecular biology · 2024
    Review
  15. Article
  16. Antioxidant and Cytotoxic Potential ofAntioxidants (Basel, Switzerland) · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Tatyana SavchenkoInstitute of Basic Biological Problems, Pushchino Scientific Center for Biological Research, Russian Academy of Sciences, 142290 Pushchino, Russia.ORCID 0000-0003-0126-4932
Evgeny DegtyaryovInstitute of Basic Biological Problems, Pushchino Scientific Center for Biological Research, Russian Academy of Sciences, 142290 Pushchino, Russia.ORCID 0000-0002-9266-7317
Yaroslav RadzyukevichInstitute of Basic Biological Problems, Pushchino Scientific Center for Biological Research, Russian Academy of Sciences, 142290 Pushchino, Russia.ORCID 0000-0002-7483-2411
Vlada BuryakFaculty of Biotechnology, Moscow State University, Leninskie Gory 1, str. 51, 119991 Moscow, Russia.ORCID 0000-0003-1946-3980

Funding

Russian Science Foundation 22-24-00489
6 · The paper itself

Abstract

For immobile plants, the main means of protection against adverse environmental factors is the biosynthesis of various secondary (specialized) metabolites. The extreme diversity and high biological activity of these metabolites determine the researchers' interest in plants as a source of therapeutic agents. Oxylipins, oxygenated derivatives of fatty acids, are particularly promising in this regard. Plant oxylipins, which are characterized by a diversity of chemical structures, can exert protective and therapeutic properties in animal cells. While the therapeutic potential of some classes of plant oxylipins, such as jasmonates and acetylenic oxylipins, has been analyzed thoroughly, other oxylipins are barely studied in this regard. Here, we present a comprehensive overview of the therapeutic potential of all major classes of plant oxylipins, including derivatives of acetylenic fatty acids, jasmonates, six- and nine-carbon aldehydes, oxy-, epoxy-, and hydroxy-derivatives of fatty acids, as well as spontaneously formed phytoprostanes and phytofurans. The presented analysis will provide an impetus for further research investigating the beneficial properties of these secondary metabolites and bringing them closer to practical applications.

Indexed as

CyclopentanesOxylipinsAlkynesAnimalsFatty Acids, UnsaturatedPlants2-hexadecynoic acidAlkynesCyclopentanesFatty Acids, Unsaturatedjasmonic acidOxylipinsacetylenic oxylipinsjasmonatesoxy-, hydroxy-, and epoxy-derivatives of fatty acidsphytoprostanes and phytofuransplant oxylipinstraumatic acid

Identifiers

PMID36498955
PMCPMC9741157

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.