Evidence map›Paper›PMID 36498895›Full record

ArticleInternational journal of molecular sciences2022

A Multichannel Fluorescent Tongue for Amyloid-

Fei Li, Lingjia Zhou, Xu Gao, Weiwei Ni, Jiabao Hu, Meicen Wu, Shouwang Chen, Jinsong Han, Jin Wu

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Fei LiState Key Laboratory of Natural Medicines, National R&D Center for Chinese Herbal Medicine Processing, Department of Food Quality and Safety, College of Engineering, China Pharmaceutical University, Nanjing 210009, China.
Lingjia ZhouState Key Laboratory of Natural Medicines, National R&D Center for Chinese Herbal Medicine Processing, Department of Food Quality and Safety, College of Engineering, China Pharmaceutical University, Nanjing 210009, China.
Xu GaoState Key Laboratory of Natural Medicines, National R&D Center for Chinese Herbal Medicine Processing, Department of Food Quality and Safety, College of Engineering, China Pharmaceutical University, Nanjing 210009, China.
Weiwei NiState Key Laboratory of Natural Medicines, National R&D Center for Chinese Herbal Medicine Processing, Department of Food Quality and Safety, College of Engineering, China Pharmaceutical University, Nanjing 210009, China.
Jiabao HuState Key Laboratory of Natural Medicines, National R&D Center for Chinese Herbal Medicine Processing, Department of Food Quality and Safety, College of Engineering, China Pharmaceutical University, Nanjing 210009, China.
Meicen WuState Key Laboratory of Natural Medicines, National R&D Center for Chinese Herbal Medicine Processing, Department of Food Quality and Safety, College of Engineering, China Pharmaceutical University, Nanjing 210009, China.
Shouwang ChenState Key Laboratory of Natural Medicines, National R&D Center for Chinese Herbal Medicine Processing, Department of Food Quality and Safety, College of Engineering, China Pharmaceutical University, Nanjing 210009, China.
Jinsong HanState Key Laboratory of Natural Medicines, National R&D Center for Chinese Herbal Medicine Processing, Department of Food Quality and Safety, College of Engineering, China Pharmaceutical University, Nanjing 210009, China.ORCID 0000-0003-1832-2641
Jin WuDepartment of Neurology, The Second Affiliated Hospital of Nanjing Medical University, Nanjing 210011, China.

Funding

Funding of Double First-Rate Discipline Innovation Team CPUQNJC22_04National Natural Science Foundation of China 32272415National Natural Science Foundation of China 52003298National Natural Science Foundation of China 82072017Natural Science Foundation of Jiangsu Province BK20200578
6 · The paper itself

Abstract

Attention has been paid to the early diagnosis of Alzheimer's disease, due to the maximum benefit acquired from the early-stage intervention and treatment. However, the sensing techniques primarily depended upon for neuroimaging and immunological assays for the detection of AD biomarkers are expensive, time-consuming and instrument dependent. Here, we developed a multichannel fluorescent tongue consisting of four fluorescent dyes and GO through electrostatic and π-π interaction. The array distinguished multiple aggregation states of 1 µM A

Indexed as

Alzheimer DiseaseAmyloid beta-PeptidesBiomarkersFluorescent DyesHumansNeuroimagingPeptide FragmentsAmyloid beta-PeptidesBiomarkersFluorescent DyesPeptide FragmentsAlzheimer’s diseaseamyloid-β proteinmachine learning algorithmmultichannelsensor array

Identifiers

PMID36498895
PMCPMC9739152

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.