Evidence map›Paper›PMID 36498893›Full record

ReviewInternational journal of molecular sciences2022

Laser Capture Microdissection: A Gear for Pancreatic Cancer Research.

Bhavana Hemantha Rao, Pavel Souček, Viktor Hlaváč

Abstract readReview
In one paragraph

Review in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Single-cell RNA sequencing offers novel perspectives in viral infection research.Frontiers in cellular and infection microbiology · 2026
    Pooled it
  2. Review
  3. Single-cell sequencing: accurate disease detection.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2026
    Review
  4. Article
  5. Article
  6. Single-Cell RNA-Sequencing: Opening New Horizons for Breast Cancer Research.International journal of molecular sciences · 2024
    Review
  7. Review
  8. Review
  9. Review
  10. Application of spatial transcriptome technologies to neurological diseases.Frontiers in cell and developmental biology · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Bhavana Hemantha RaoBiomedical Center, Faculty of Medicine in Pilsen, Charles University, 306 05 Pilsen, Czech Republic.ORCID 0000-0001-9559-5606
Pavel SoučekBiomedical Center, Faculty of Medicine in Pilsen, Charles University, 306 05 Pilsen, Czech Republic.ORCID 0000-0002-4294-6799
Viktor HlaváčBiomedical Center, Faculty of Medicine in Pilsen, Charles University, 306 05 Pilsen, Czech Republic.ORCID 0000-0003-0695-0552

Funding

Czech Health Research Council NU21-07-00247
6 · The paper itself

Abstract

The advancement in molecular techniques has been attributed to the quality and significance of cancer research. Pancreatic cancer (PC) is one of the rare cancers with aggressive behavior and a high mortality rate. The asymptomatic nature of the disease until its advanced stage has resulted in late diagnosis as well as poor prognosis. The heterogeneous character of PC has complicated cancer development and progression studies. The analysis of bulk tissues of the disease was insufficient to understand the disease, hence, the introduction of the single-cell separating technique aided researchers to decipher more about the specific cell population of tumors. This review gives an overview of the Laser Capture Microdissection (LCM) technique, one of the single-cell separation methods used in PC research.

Indexed as

Carcinoma, Pancreatic DuctalPancreatic NeoplasmsHumansLaser Capture MicrodissectionPancreashypoxiaintraductal papillary mucinous neoplasm (IPMN)Laser Capture Microdissection (LCM)metastasispancreatic cancersingle-cell separation

Identifiers

PMID36498893
PMCPMC9741023

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.