Evidence map›Paper›PMID 36498874›Full record

ArticleInternational journal of molecular sciences2022

Effects of Corchorusoside C on NF-κB and PARP-1 Molecular Targets and Toxicity Profile in Zebrafish.

Nathan P Mirtallo Ezzone, Gerardo D Anaya-Eugenio, Ermias Mekuria Addo, Yulin Ren, A Douglas Kinghorn, Esperanza J Carcache de Blanco

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.7field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
  2. Article
  3. Bioactive compounds isolated from the bark ofPhytochemistry letters · 2024
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Nathan P Mirtallo EzzoneDivision of Medicinal Chemistry and Pharmacognosy, College of Pharmacy, The Ohio State University, Columbus, OH 43210, USA.
Gerardo D Anaya-EugenioDivision of Medicinal Chemistry and Pharmacognosy, College of Pharmacy, The Ohio State University, Columbus, OH 43210, USA.
Ermias Mekuria AddoDivision of Medicinal Chemistry and Pharmacognosy, College of Pharmacy, The Ohio State University, Columbus, OH 43210, USA.
Yulin RenDivision of Medicinal Chemistry and Pharmacognosy, College of Pharmacy, The Ohio State University, Columbus, OH 43210, USA.ORCID 0000-0003-3667-1466
A Douglas KinghornDivision of Medicinal Chemistry and Pharmacognosy, College of Pharmacy, The Ohio State University, Columbus, OH 43210, USA.ORCID 0000-0002-6647-8707
Esperanza J Carcache de BlancoDivision of Medicinal Chemistry and Pharmacognosy, College of Pharmacy, The Ohio State University, Columbus, OH 43210, USA.
The Ohio State University · US

Funding

Project 3:Isolation Chemistry of Filamentous Fungi and Biological EvaluationP01CA125066 · NCI · OHIO STATE UNIVERSITY · PI JIMMY ORJALA · 2007 to 2026
$27.2M
CREATES fellowship (Ohio State University Comprehensive Cancer Center), Jack Beal Endow-ment funds, and in part by program project grant P01 CA125066 and by P01 CA125066-S12 from the National Cancer Institute, National Institutes of Health P01 CA125066-S12
6 · The paper itself

Abstract

The present study aims to continue the study of corchorusoside C (

Indexed as

NF-kappa BPoly (ADP-Ribose) Polymerase-1Prostatic NeoplasmsAnimalsCaspasesCell Line, TumorHumansMaleMolecular Docking SimulationTumor Suppressor Protein p53ZebrafishZebrafish ProteinsCaspasesNF-kappa BParp1 protein, zebrafishPoly (ADP-Ribose) Polymerase-1Tumor Suppressor Protein p53Zebrafish Proteinscaspase-1corchorusoside CNF-κBPARP-1zebrafish

Identifiers

PMID36498874
PMCPMC9739208
OpenAlexW4309711333

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.