Evidence map›Paper›PMID 36498781›Full record

ReviewJournal of clinical medicine2022

Antibiotics Use in COVID-19 Patients: A Systematic Literature Review.

Guido Granata, Francesco Schiavone, Giuseppe Pipitone, Fabrizio Taglietti, Nicola Petrosillo

Open access · goldAbstract readReview
In one paragraph

Review in Journal of clinical medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed
4.3field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 47 citations in OpenAlex.

  1. Article
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  15. Article
  16. Trends in inpatient antibiotic use in Indonesia and the Philippines during the COVID-19 pandemic.Antimicrobial stewardship & healthcare epidemiology : ASHE · 2025
    Article
  17. Article
  18. Article
  19. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 1 country.

Guido GranataClinical and Research Department for Infectious Diseases, National Institute for Infectious Diseases L. Spallanzani, IRCCS, 00149 Rome, Italy.ORCID 0000-0001-5796-0545
Francesco SchiavoneDivers and Raiders Group Command "Teseo Tesei" COMSUBIN, Medical Service, Italian Navy, 19025 Portovenere, Italy.ORCID 0000-0002-9362-1150
Giuseppe PipitoneInfectious Disease Unit, ARNAS Civico-Di Cristina, Piazza Leotta, 5, 90100 Palermo, Italy.ORCID 0000-0002-3408-4877
Fabrizio TagliettiClinical and Research Department for Infectious Diseases, National Institute for Infectious Diseases L. Spallanzani, IRCCS, 00149 Rome, Italy.
Nicola PetrosilloFondazione Policlinico Universitario Campus Bio-Medico, 00128 Rome, Italy.ORCID 0000-0002-2585-7567
Istituto Nazionale per le Malattie Infettive Lazzaro Spallanzani · ITAnsaldo (Italy) · ITCampus Bio Medico University Hospital · ITRina Services (Italy) · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The issue of bacterial infections in COVID-19 patients has received increasing attention among scientists. Antibiotics were widely prescribed during the early phase of the pandemic. We performed a literature review to assess the reasons, evidence and practices on the use of antibiotics in COVID-19 in- and outpatients. Published articles providing data on antibiotics use in COVID-19 patients were identified through computerized literature searches on the MEDLINE and SCOPUS databases. Searching the MEDLINE database, the following search terms were adopted: ((antibiotic) AND (COVID-19)). Searching the SCOPUS database, the following search terms were used: ((antibiotic treatment) AND (COVID-19)). The risk of bias in the included studies was not assessed. Both quantitative and qualitative information were summarized by means of textual descriptions. Five-hundred-ninety-three studies were identified, published from January 2020 to 30 October 2022. Thirty-six studies were included in this systematic review. Of the 36 included studies, 32 studies were on the use of antibiotics in COVID-19 inpatients and 4 on antibiotic use in COVID-19 outpatients. Apart from the studies identified and included in the review, the main recommendations on antibiotic treatment from 5 guidelines for the clinical management of COVID-19 were also summarized in a separate paragraph. Antibiotics should not be prescribed during COVID-19 unless there is a strong clinical suspicion of bacterial coinfection or superinfection.

Indexed as

antibioticsantibiotics use in COVID-19 patientsantimicrobialsbacterial coinfectionbacterial infectionsCOVID-19 inpatientsCOVID-19 outpatientsCOVID-19 pandemicguidelines for the clinical management of COVID-19systematic review

Identifiers

PMID36498781
PMCPMC9739751
OpenAlexW4311289634

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.