Evidence map›Paper›PMID 36498697›Full record

ArticleJournal of clinical medicine2022

Identification of Neural Mechanisms in First Single-Sweep Analysis in oVEMPs and Novel Normative Data.

Dietmar J Hecker, Hans Scherer, Uwe Schönfeld, Laura Jerono, Armand Koch, Anna-Katharina Rink, Lisa Schulte-Goebel, Maximilian Linxweiler, Mathias Fousse, Alessandro Bozzato and 1 more

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Article in Journal of clinical medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

11 authors.

Dietmar J HeckerDepartment for Otorhinolaryngology, Head and Neck Surgery, Saarland University Medical Center, 66421 Homburg, Germany.ORCID 0000-0002-4944-0846
Hans SchererCharité University Medicine, 13353 Berlin, Germany.
Uwe SchönfeldDepartment of Otorhinolaryngology, Head and Neck Surgery, Charité University Medicine, 13353 Berlin, Germany.ORCID 0000-0001-7663-2387
Laura JeronoDepartment for Otorhinolaryngology, Head and Neck Surgery, Saarland University Medical Center, 66421 Homburg, Germany.ORCID 0000-0002-3908-0365
Armand KochDepartment for Otorhinolaryngology, Head and Neck Surgery, Saarland University Medical Center, 66421 Homburg, Germany.
Anna-Katharina RinkDepartment for Otorhinolaryngology, Head and Neck Surgery, Saarland University Medical Center, 66421 Homburg, Germany.
Lisa Schulte-GoebelDepartment for Otorhinolaryngology, Head and Neck Surgery, Saarland University Medical Center, 66421 Homburg, Germany.
Maximilian LinxweilerDepartment for Otorhinolaryngology, Head and Neck Surgery, Saarland University Medical Center, 66421 Homburg, Germany.ORCID 0000-0002-5028-9282
Mathias FousseDepartment of Neurology, Saarland University Medical Center, 66421 Homburg, Germany.
Alessandro BozzatoDepartment for Otorhinolaryngology, Head and Neck Surgery, Saarland University Medical Center, 66421 Homburg, Germany.ORCID 0000-0002-9648-8834
Bernhard SchickDepartment for Otorhinolaryngology, Head and Neck Surgery, Saarland University Medical Center, 66421 Homburg, Germany.

Funding

Federal Ministry of Education and Research 13GW0286B
6 · The paper itself

Abstract

backgroundBone-conducted (BC) VEMPs provide important tools for measuring otolith function. However, two major drawbacks of this method are encountered in clinical practice-small n10 amplitude and averaging technique. In this study, we present the results of a new VEMP setup measuring technique combined with a novel single-sweep analysis.

methodsThe study included BC oVEMP data from 92 participants for the evaluation of normative data using a novel analysis technique. For evaluating test-retest reliability, the intraclass correlation coefficient (ICC) was used.

resultsWe found significant n10 amplitude differences in single-sweep analyses after the first and second measurements. Thereby, mathematical analyses of the head movement did not show any differences in the first or second measurements. The normative n10 amplitude was 20.66 µV with an asymmetric ratio (AR) of 7%. The new value of late shift difference (LSD) was 0.01 ms. The test retest-reliability showed good to excellent ICC results in 9 out of 10 measurements.

conclusionsOur results support a phenomenon in single-sweep analysis of the first stimuli independent of head movement and signal morphology. Furthermore, the values obtained with the new measurement method appear to be more sensitive and may allow an extended diagnostic range due to the new parameter LSD.

Indexed as

bone-conductedefferent mechanismn10 amplitude and latencynovel algorithmsoVEMPssingle sweepssynchronization

Identifiers

PMID36498697
PMCPMC9738122

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