Evidence map›Paper›PMID 36498393›Full record

Trial reportInternational journal of environmental research and public health2022

Resistance Training Improves Sleep and Anti-Inflammatory Parameters in Sarcopenic Older Adults: A Randomized Controlled Trial.

Helton de Sá Souza, Camila Maria de Melo, Ronaldo Delmonte Piovezan, Rafael Eduardo Eustórgio Pinheiro Chagas Miranda, Miguel Araujo Carneiro-Junior, Bruno Moreira Silva, Ronaldo Vagner Thomatieli-Santos, Sergio Tufik, Dalva Poyares, Vânia D'Almeida

Registry-linked trialAbstract readRandomized Controlled Trial
In one paragraph

Trial report in International journal of environmental research and public health, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07234812 (The Effects of Tailored Resistance Exercise on Sleep Quality in Relation to Chronotype), which is not on this map. Cited by 27 papers, 9 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 9 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07234812 nanot yet recruitingnot on this mapstarted 2025, after this paper: background citation

The Effects of Tailored Resistance Exercise on Sleep Quality in Relation to Chronotype

TypeinterventionalSponsorMedipol UniversityRan2025 to 2026Enrolled64ConditionsPhysical Therapy, Resistance Exercise, Sleep Disturbances, Sleep QualityArmsModerate-Intensity Resistance Exercise Program
3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 9 syntheses or guidelines pooled it.

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  8. Effects of different types of exercise on sleep quality based on Pittsburgh Sleep Quality Index in middle-aged and older adults: a network meta-analysis.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Helton de Sá SouzaDepartment of Physical Education, Universidade Federal de Viçosa, Viçosa 36570-900, MG, Brazil.ORCID 0000-0003-0525-5371
Camila Maria de MeloDepartment of Nutrition, Universidade Federal de Lavras, Lavras 37200-000, MG, Brazil.
Ronaldo Delmonte PiovezanDepartment of Psychobiology, Universidade Federal de São Paulo, São Paulo 04023-062, SP, Brazil.
Rafael Eduardo Eustórgio Pinheiro Chagas MirandaDepartment of Psychobiology, Universidade Federal de São Paulo, São Paulo 04023-062, SP, Brazil.
Miguel Araujo Carneiro-JuniorDepartment of Physical Education, Universidade Federal de Viçosa, Viçosa 36570-900, MG, Brazil.
Bruno Moreira SilvaDepartment of Physiology, Universidade Federal de São Paulo, São Paulo 04023-062, SP, Brazil.
Ronaldo Vagner Thomatieli-SantosDepartment of Biosciences, Universidade Federal de São Paulo, Santos 11015-020, SP, Brazil.ORCID 0000-0001-7010-2799
Sergio TufikDepartment of Psychobiology, Universidade Federal de São Paulo, São Paulo 04023-062, SP, Brazil.
Dalva PoyaresDepartment of Psychobiology, Universidade Federal de São Paulo, São Paulo 04023-062, SP, Brazil.
Vânia D'AlmeidaDepartment of Psychobiology, Universidade Federal de São Paulo, São Paulo 04023-062, SP, Brazil.ORCID 0000-0003-0947-5312

Funding

Conselho Nacional de Desenvolvimento Científico e Tecnológico 165071/2015-0Fundação de Amparo à Pesquisa do Estado de São Paulo 2016/00521-9
6 · The paper itself

Abstract

Sleep and exercise have an important role in the development of several inflammation-related diseases, including sarcopenia. Objective: To investigate the effects of 12 weeks of resistance exercise training on sleep and inflammatory status in sarcopenic patients. Methods: A randomized controlled trial comparing resistance exercise training (RET) with a control (CTL) was conducted. Outcomes were obtained by physical tests, polysomnography, questionnaires, isokinetic/isometric dynamometry tests, and biochemical analysis. Results: Time to sleep onset (sleep latency) was reduced in the RET group compared to the CTL group (16.09 ± 15.21 vs. 29.98 ± 16.09 min; p = 0.04) after the intervention. The percentage of slow-wave sleep (N3 sleep) was increased in the RET group (0.70%, CI: 7.27−16.16 vs. −4.90%, CI: 7.06−16.70; p = 0.04) in an intention to treat analysis. Apnea/hour was reduced in the RET group (16.82 ± 14.11 vs. 7.37 ± 7.55; p = 0.001) and subjective sleep quality was improved compared to the CTL (−1.50; CI: 2.76−6.14 vs. 0.00; CI: 1.67−3.84 p = 0.02) in an intention-to-treat analysis. Levels of interleukin-10 (IL-10) (2.13 ± 0.80 vs. 2.51 ± 0.99; p < 0.03) and interleukin-1 receptor antagonist (IL-1ra) (0.99 ± 0.10 vs. 0.99 ± 0.10 ng/mL; p < 0.04; delta variation) were increased in the RET group. Conclusions: RET improves sleep parameters linked to muscle performance, possibly due to an increase in anti-inflammatory markers in older sarcopenic patients.

Indexed as

Resistance TrainingSarcopeniaAgedAnti-Inflammatory AgentsHumansMuscle, SkeletalMuscle StrengthSleepAnti-Inflammatory Agentsagingphysical exerciseskeletal musclesleep quality

Identifiers

PMID36498393
PMCPMC9736460

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.