ArticleInternational journal of environmental research and public health2022
Sex Differences in Heart Failure Mortality with Preserved, Mildly Reduced and Reduced Ejection Fraction: A Retrospective, Single-Center, Large-Cohort Study.
Article in International journal of environmental research and public health, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed.
- Trial
- Demographics and mortality trends of hypertensive heart failure in the United States, 2006-2020: Insights from the CDC WONDER database.The Journal of international medical research · 2026Observational
- Sex and Gender Aspects in New-Onset Heart Failure Prognosis: A Review of Recent Advances.Current heart failure reports · 2025Review
- Emerging trends in cardiovascular diseases: the impact of ferroptosis and cuproptosis on cardiomyocyte death.Molecular and cellular biochemistry · 2025Review
- Do gender differences matter in Acute Heart Failure? Insights from Indian College of Cardiology - National Heart Failure Registry, India.International journal of cardiology. Cardiovascular risk and prevention · 2025Article
- Sex-Specific Risk Factors and Predictors of Major Adverse Cardiac and Cerebrovascular Events in Heart Failure with Preserved Ejection Fraction with SARS-CoV-2 Infection: A Nationwide Analysis.Journal of clinical medicine · 2025Article
- Sex differences in heart failure mortality by ejection fraction subtype: a single-center, retrospective cohort study.Frontiers in cardiovascular medicine · 2025Article
- Demographic trends and disparities in mortality related to coexisting heart failure and diabetes mellitus among older adults in the United States between 1999 and 2020: A retrospective population-based cohort study from the CDC WONDER database.International journal of cardiology. Cardiovascular risk and prevention · 2024Article
- Sex differences of visceral fat with cardiac structure and function in type 2 diabetes: A cross-sectional study.Journal of diabetes · 2024Article
- Sex difference in human diseases: mechanistic insights and clinical implications.Signal transduction and targeted therapy · 2024Review
- Differential Effect of Sex on Mortality According to Age in Heart Failure.Journal of the American Heart Association · 2024Article
- Sex Differences in Prognosis of Heart Failure Due to Ischemic and Nonischemic Cardiomyopathy.Journal of clinical medicine · 2023Article
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Authors and funding
10 authors.
Funding
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Abstract
backgroundHeart failure (HF) is one of the leading causes of death worldwide. Studies show that women have better survival rates than men despite higher hospitalizations. However, little is known about differences in mortality and predictors of death in women and men with HF with preserved (HFpEF), mildly reduced (HFmrEF), and reduced ejection fraction (HFrEF).
methodsFrom February 2017 to September 2020, mortality and predictors of death were analyzed in women and men with HF. Baseline data included clinical characteristics and echocardiographic findings.
resultsA total of 11,282 patients, 63.9 ± 14.4 years, including 6256 (55.4%) males, were studied. Females were older, had a higher baseline mean left ventricular ejection fraction (LVEF) and lower left ventricular diastolic diameter. During follow-ups, 1375 (22%) men and 925 (18.4%) women died. Cumulative incidence of death was higher in men with HFrEF but similar for HFmrEF and HFpEF. Cox regression for death showed renal dysfunction, stroke, diabetes, atrial fibrillation, age, LVEF, valve disease, MI, and hypertensive CMP as independent death predictors for all HF patients.
conclusionsWomen had a better prognosis than men in HFrEF and similar mortality for HFmrEF and HFpEF, but sex was not an independent predictor of death for all HF subtypes.
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