Evidence map›Paper›PMID 36498153›Full record

ReviewInternational journal of environmental research and public health2022

Using Tree-Based Machine Learning for Health Studies: Literature Review and Case Series.

Liangyuan Hu, Lihua Li

Open access · goldAbstract readReview
In one paragraph

Review in International journal of environmental research and public health, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
7.6field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 38 citations in OpenAlex.

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  13. A multidimensional analysis of the 21Scientific reports · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Liangyuan HuDepartment of Biostatistics and Epidemiology, Rutgers University, Piscataway, NJ 08854, USA.ORCID 0000-0002-4067-892X
Lihua LiDepartment of Population Health Science and Policy, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.ORCID 0000-0003-3154-9576
Icahn School of Medicine at Mount Sinai · USRutgers, The State University of New Jersey · US

Funding

Bayesian machine learning for causal inference with incomplete longitudinal covariates and censored survival outcomesR01HL159077 · NHLBI · RUTGERS BIOMEDICAL AND HEALTH SCIENCES · PI Liangyuan Hu · 2022 to 2026
$3.3M
Flexible Bayesian approaches to causal inference with multilevel survival data and multiple treatmentsR21CA245855 · NCI · RBHS-SCHOOL OF PUBLIC HEALTH · PI HU, LIANGYUAN · 2020 to 2020
$459k
National Institute of Health 1R01HL159077-01A1NCI NIH HHS R21 CA245855NHLBI NIH HHS R01 HL159077
6 · The paper itself

Abstract

Tree-based machine learning methods have gained traction in the statistical and data science fields. They have been shown to provide better solutions to various research questions than traditional analysis approaches. To encourage the uptake of tree-based methods in health research, we review the methodological fundamentals of three key tree-based machine learning methods: random forests, extreme gradient boosting and Bayesian additive regression trees. We further conduct a series of case studies to illustrate how these methods can be properly used to solve important health research problems in four domains: variable selection, estimation of causal effects, propensity score weighting and missing data. We exposit that the central idea of using ensemble tree methods for these research questions is accurate prediction via flexible modeling. We applied ensemble trees methods to select important predictors for the presence of postoperative respiratory complication among early stage lung cancer patients with resectable tumors. We then demonstrated how to use these methods to estimate the causal effects of popular surgical approaches on postoperative respiratory complications among lung cancer patients. Using the same data, we further implemented the methods to accurately estimate the inverse probability weights for a propensity score analysis of the comparative effectiveness of the surgical approaches. Finally, we demonstrated how random forests can be used to impute missing data using the Study of Women's Health Across the Nation data set. To conclude, the tree-based methods are a flexible tool and should be properly used for health investigations.

Indexed as

Lung NeoplasmsMachine LearningBayes TheoremFemaleHumansPropensity Scorecausal inferenceensemble methodsmissing datasensitivity analysisvariable selection

Identifiers

PMID36498153
PMCPMC9736500
OpenAlexW4311053661

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.