Evidence map›Paper›PMID 36497991›Full record

ArticleInternational journal of environmental research and public health2022

Knowledge and Attitudes of Guam Residents towards Cancer Clinical Trial Participation.

Munirih R Taafaki, Amy C Brown, Kevin D Cassel, John J Chen, Eunjung Lim, Yvette C Paulino

Abstract read
In one paragraph

Article in International journal of environmental research and public health, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Munirih R TaafakiDepartment of Quantitative Health Sciences, John A. Burns School of Medicine, University of Hawai'i at Mānoa, Honolulu, HI 96813, USA.
Amy C BrownDepartment of Quantitative Health Sciences, John A. Burns School of Medicine, University of Hawai'i at Mānoa, Honolulu, HI 96813, USA.
Kevin D CasselPopulation Sciences in the Pacific Program, University of Hawai'i Cancer Center, Honolulu, HI 96813, USA.ORCID 0000-0001-6167-9959
John J ChenDepartment of Quantitative Health Sciences, John A. Burns School of Medicine, University of Hawai'i at Mānoa, Honolulu, HI 96813, USA.
Eunjung LimDepartment of Quantitative Health Sciences, John A. Burns School of Medicine, University of Hawai'i at Mānoa, Honolulu, HI 96813, USA.
Yvette C PaulinoSchool of Health, University of Guam, Mangilao, GU 96923, USA.

Funding

The Role of gp120 on Cardiovascular Disease in People Living with HIVU54MD007601 · NIMHD · UNIVERSITY OF HAWAII AT MANOA · PI Benjamin C. Fogelgren · 2017 to 2026
$59.5M
University of Guam/Cancer Research Center of Hawaii Partnership (2 of 2)U54CA143728 · NCI · UNIVERSITY OF GUAM · PI RACHAEL T LEON GUERRERO · 2009 to 2026
$20.1M
University of Guam/Cancer Research Center of Hawaii Partnership (1 of 2)U54CA143727 · NCI · UNIVERSITY OF HAWAII AT MANOA · PI LYNNE R WILKENS · 2009 to 2026
$19.1M
Tracking and Evaluation CoreU54GM138062 · NIGMS · UNIVERSITY OF HAWAII AT MANOA · PI SY, ANGELA U · 2021 to 2025
$15.5M
NCI NIH HHS U54 CA143727NCI NIH HHS U54 CA143728NIGMS NIH HHS U54 GM138062NIMHD NIH HHS U54 MD007601
6 · The paper itself

Abstract

(1) Background: Currently there are no cancer clinical trials in Guam, where CHamoru people suffer the highest rates of cancer mortality, and interest to do so is growing. This study investigated the knowledge and attitudes of Guam residents towards cancer clinical trial participation prior to implementation. (2) Methods: A telephone survey was developed, tested, and conducted among Guam resident adults, 18 years of age and older. Survey questions were summarized by descriptive statistics. Logistic regression models were used to investigate the associations between Guam residents' demographics and their clinical trial knowledge and attitudes. Adjusted odds ratios (aOR) and associated 95% confidence intervals (CI) were calculated. (3) Results: One hundred fifty-two people participated in the survey, most of whom were CHamoru (47.0%). Fifty-three percent had heard the term 'clinical trial'; 73.7% would take part in a trial if they had cancer; and 59.9% believed they would receive good quality treatment from a trial offered in Guam. CHamoru were more likely than Whites to associate out-of-pocket expenses with clinical trial participation (aOR = 5.34, 95% CI = 1.68-17.00). Physician ethnicity was important to 30% of non-Whites and significantly associated with those who spoke a language other than English (aOR = 3.40, 95% CI = 1.29-8.95). Most people (65.0%) did not believe clinical trials participants were 'guinea pigs'. (4) Conclusion: Though knowledge about cancer clinical trials is limited, attitudes were primarily positive towards participating in cancer clinical trials offered in Guam. Future delivery of cancer clinical trials will benefit from identifying potential barriers to recruitment and adopting an approach suited to Guam's population.

Indexed as

Health Knowledge, Attitudes, PracticeNeoplasmsPatient ParticipationClinical Trials as TopicEthnicityGuamHumansattitudescancerclinical trialGuamknowledge

Identifiers

PMID36497991
PMCPMC9736365

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.