Evidence map›Paper›PMID 36497359›Full record

ReviewCancers2022

Dietary Polyphenol Intake and Gastric Cancer: A Systematic Review and Meta-Analysis.

Marcela de Araújo Fagundes, Alex Richard Costa Silva, Gisele Aparecida Fernandes, Maria Paula Curado

Open access · goldAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Cancers, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 4 pooled it
1.6field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 4 syntheses or guidelines pooled it, 18 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Review
  6. Review
  7. Paradigm Shift in Gastric Cancer Prevention: Harnessing the Potential ofInternational journal of molecular sciences · 2023
    Article
  8. Article
  9. Review
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Marcela de Araújo FagundesGraduate Program of A.C. Camargo Cancer Center, R. Professor Antônio Prudente, 211, São Paulo 01509-900 , Brazil.ORCID 0000-0003-0662-4810
Alex Richard Costa SilvaGraduate Program of A.C. Camargo Cancer Center, R. Professor Antônio Prudente, 211, São Paulo 01509-900 , Brazil.
Gisele Aparecida FernandesGroup of Epidemiology and Statistics on Cancer, International Research Center, A.C. Camargo Cancer Center, R. Tagua 440, Sao Paulo 01508-010, Brazil.
Maria Paula CuradoGroup of Epidemiology and Statistics on Cancer, International Research Center, A.C. Camargo Cancer Center, R. Tagua 440, Sao Paulo 01508-010, Brazil.
AC Camargo Hospital · BR

Funding

São Paulo Research Foundation 2014/26897-0
6 · The paper itself

Abstract

backgroundPhenolic compound consumption may have a protective effect against gastric cancer (GC). Most GC studies focus on the flavonoids class, but results are conflicting and knowledge gaps remain for other classes and total polyphenol intake. This study aimed to assess the association between polyphenol intake (total, flavonoids, and other classes) and GC.

methodsIn this systematic review and meta-analysis, the PubMed, Embase, Scopus, LILACS, Web of Science, and OpenGrey databases were searched for studies published up to 20 March 2022. Case-control and cohort studies analyzing the association between polyphenol intake and GC were included. For the meta-analysis, pooled summary estimates were calculated using a random-effects model, and the estimates extracted adjusted for most variables. Subgroup analyses were performed for subclass (e.g., flavonoids and other classes), sex, geographical area, study design, anatomical subtype, histological subtype, family history of GC and fruit and/or vegetable intake. The study was registered with PROSPERO (#CRD42022306014).

findingsThe search identified 2752 records, of which 19 studies published during the period 1999-2021 including a total of 1,197,857 subjects were eligible. Polyphenol consumption reduced GC risk by 29% (RR = 0.71; 95% CI: 0.62-0.81; I

conclusionsDietary polyphenol intake decreased GC risk. The reduction was greatest in females. Most previous studies were carried out in Europe and Asia. Further studies investigating polyphenol consumption and GC in Latin American populations are warranted.

Indexed as

dietary polyphenol intakegastric cancermeta-analysissystematic review

Identifiers

PMID36497359
PMCPMC9737802
OpenAlexW4311282197

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.