Evidence map›Paper›PMID 36497279›Full record

ArticleCancers2022

Identification of Risk Factors for Sexual Dysfunction after Multimodal Therapy of Locally Advanced Rectal Cancer and Their Impact on Quality of Life: A Single-Center Trial.

Peter Tschann, Markus Weigl, Thomas Brock, Jürgen Frick, Oliver Sturm, Jaroslav Presl, Tarkan Jäger, Michael Weitzendorfer, Philipp Schredl, Patrick Clemens and 8 more

Abstract read
In one paragraph

Article in Cancers, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Sexual dysfunction outcomes and reporting disparities after multimodal treatment for rectal cancer: A systematic review and narrative synthesis.Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland · 2026
    Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Peter TschannDepartment of General and Thoracic Surgery, Academic Teaching Hospital, 6800 Feldkirch, Austria.ORCID 0000-0003-3950-0347
Markus WeiglDepartment of General and Thoracic Surgery, Academic Teaching Hospital, 6800 Feldkirch, Austria.
Thomas BrockDepartment of General and Thoracic Surgery, Academic Teaching Hospital, 6800 Feldkirch, Austria.
Jürgen FrickDepartment of General and Thoracic Surgery, Academic Teaching Hospital, 6800 Feldkirch, Austria.
Oliver SturmDepartment of General and Thoracic Surgery, Academic Teaching Hospital, 6800 Feldkirch, Austria.
Jaroslav PreslDepartment of Surgery, Paracelsus Medical University, 5020 Salzburg, Austria.ORCID 0000-0002-2899-6706
Tarkan JägerDepartment of Surgery, Paracelsus Medical University, 5020 Salzburg, Austria.ORCID 0000-0002-2390-0226
Michael WeitzendorferDepartment of Surgery, Paracelsus Medical University, 5020 Salzburg, Austria.ORCID 0000-0003-1657-7405
Philipp SchredlDepartment of Surgery, Paracelsus Medical University, 5020 Salzburg, Austria.
Patrick ClemensDepartment of Radio-Oncology, Academic Teaching Hospital, 6800 Feldkirch, Austria.ORCID 0000-0002-0984-2605
Helmut EiterDepartment of Radio-Oncology, Academic Teaching Hospital, 6800 Feldkirch, Austria.
Philipp SzeverinskiInstitute of Medical Physics, Academic Teaching Hospital, 6800 Feldkirch, Austria.
Christian AttenbergerInstitute of Medical Physics, Academic Teaching Hospital, 6800 Feldkirch, Austria.
Veronika TschannDepartment of Internal Medicine II, Academic Teaching Hospital, 6800 Feldkirch, Austria.
Walter BrunnerDepartment of General, Visceral, Endocrine and Transplant Surgery, Cantonal Hospital of St. Gallen, 9000 St. Gallen, Switzerland.
Alexander De VriesDepartment of Radio-Oncology, Academic Teaching Hospital, 6800 Feldkirch, Austria.
Klaus EmmanuelDepartment of Surgery, Paracelsus Medical University, 5020 Salzburg, Austria.
Ingmar KönigsrainerDepartment of General and Thoracic Surgery, Academic Teaching Hospital, 6800 Feldkirch, Austria.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeSexual function is crucial for the quality of life and can be highly affected by preoperative therapy and surgery. The aim of this study was to identify potential risk factors for poor sexual function and quality of life.

methodsFemale patients were asked to complete the Female Sexual Function Index (FSFI-6). Male patients were demanded to answer the International Index of Erectile Function (IIEF-5).

resultsIn total, 79 patients filled in the questionary, yielding a response rate of 41.57%. The proportion of women was represented by 32.91%, and the median age was 76.0 years (66.0-81.0). Sexual dysfunction appeared in 88.46% of female patients. Severe erectile dysfunction occurred in 52.83% of male patients. Univariate analysis showed female patients (OR: 0.17, 95%CI: 0.05-0.64,

conclusionHigher Age, female sex, distal tumors and extensive surgery (APR, ISR) are revealed risk factors for SD in this study. Quality of life was only affected in the case of APR or ISR.

Indexed as

multimodal therapyquality of liferectal cancersexual dysfunction

Identifiers

PMID36497279
PMCPMC9736520

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.