Evidence map›Paper›PMID 36497228›Full record

ReviewCancers2022

Ten Years of CRISPRing Cancers In Vitro.

Davide Capoferri, Serena Filiberti, Jessica Faletti, Camilla Tavani, Roberto Ronca

Open access · goldAbstract readReview
In one paragraph

Review in Cancers, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Davide CapoferriSection of Experimental Oncology and Immunology, Department of Molecular and Translational Medicine, University of Brescia, 25121 Brescia, Italy.ORCID 0000-0002-1251-8136
Serena FilibertiSection of Experimental Oncology and Immunology, Department of Molecular and Translational Medicine, University of Brescia, 25121 Brescia, Italy.ORCID 0000-0001-9795-2638
Jessica FalettiSection of Experimental Oncology and Immunology, Department of Molecular and Translational Medicine, University of Brescia, 25121 Brescia, Italy.
Camilla TavaniSection of Experimental Oncology and Immunology, Department of Molecular and Translational Medicine, University of Brescia, 25121 Brescia, Italy.
Roberto RoncaSection of Experimental Oncology and Immunology, Department of Molecular and Translational Medicine, University of Brescia, 25121 Brescia, Italy.ORCID 0000-0001-8979-7068
University of Brescia · IT

Funding

Italian Association for Cancer Research IG 2019 - ID. 23151
6 · The paper itself

Abstract

Cell lines have always constituted a good investigation tool for cancer research, allowing scientists to understand the basic mechanisms underlying the complex network of phenomena peculiar to the transforming path from a healthy to cancerous cell. The introduction of CRISPR in everyday laboratory activity and its relative affordability greatly expanded the bench lab weaponry in the daily attempt to better understand tumor biology with the final aim to mitigate cancer's impact in our lives. In this review, we aim to report how this genome editing technique affected in the in vitro modeling of different aspects of tumor biology, its several declinations, and analyze the advantages and drawbacks of each of them.

Indexed as

cancerCRISPRgenome editinghallmarkin vitrotechnology

Identifiers

PMID36497228
PMCPMC9738354
OpenAlexW4309721602

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.