Evidence map›Paper›PMID 36497223›Full record

ArticleCancers2022

Prospectively Accelerated T2-Weighted Imaging of the Prostate by Combining Compressed SENSE and Deep Learning in Patients with Histologically Proven Prostate Cancer.

Felix N Harder, Kilian Weiss, Thomas Amiel, Johannes M Peeters, Robert Tauber, Sebastian Ziegelmayer, Egon Burian, Marcus R Makowski, Andreas P Sauter, Jürgen E Gschwend and 2 more

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Cancers, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05820113 (Deep Learning Super Resolution Reconstruction for Fast and Motion Robust T2-weighted Prostate MRI), which is not on this map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
5.0field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05820113 nacompletednot on this map

Deep Learning Super Resolution Reconstruction for Fast and Motion Robust T2-weighted Prostate MRI

TypeinterventionalSponsorUniversity Hospital, BonnRan2022 to 2022Enrolled109ConditionsProstate Cancer, Multiparametric MRIArmsDeep learning based reconstruction of T2-TSE sequence
3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 36 citations in OpenAlex.

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  8. Utility of Thin-slice Single-shot T2-weighted MR Imaging with Deep Learning Reconstruction as a Protocol for Evaluating Pancreatic Cystic Lesions.Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 2 countries.

Felix N HarderInstitute of Diagnostic and Interventional Radiology, School of Medicine, Technical University of Munich, Ismaninger Str. 22, 81675 Munich, Germany.ORCID 0000-0002-3182-5924
Kilian WeissPhilips GmbH, Röntgenstrasse 22, 22335 Hamburg, Germany.ORCID 0000-0003-4295-4585
Thomas AmielDepartment of Urology, Technical University of Munich, Ismaninger Str. 22, 81675 Munich, Germany.
Johannes M PeetersPhilips Healthcare, Veenpluis 4-6, Building QR-0.113, 5684 Best, The Netherlands.ORCID 0000-0001-6639-0863
Robert TauberDepartment of Urology, Technical University of Munich, Ismaninger Str. 22, 81675 Munich, Germany.
Sebastian ZiegelmayerInstitute of Diagnostic and Interventional Radiology, School of Medicine, Technical University of Munich, Ismaninger Str. 22, 81675 Munich, Germany.
Egon BurianInstitute of Diagnostic and Interventional Radiology, School of Medicine, Technical University of Munich, Ismaninger Str. 22, 81675 Munich, Germany.ORCID 0000-0003-0428-8569
Marcus R MakowskiInstitute of Diagnostic and Interventional Radiology, School of Medicine, Technical University of Munich, Ismaninger Str. 22, 81675 Munich, Germany.
Andreas P SauterInstitute of Diagnostic and Interventional Radiology, School of Medicine, Technical University of Munich, Ismaninger Str. 22, 81675 Munich, Germany.
Jürgen E GschwendDepartment of Urology, Technical University of Munich, Ismaninger Str. 22, 81675 Munich, Germany.
Dimitrios C KarampinosInstitute of Diagnostic and Interventional Radiology, School of Medicine, Technical University of Munich, Ismaninger Str. 22, 81675 Munich, Germany.ORCID 0000-0003-4922-3662
Rickmer F BrarenInstitute of Diagnostic and Interventional Radiology, School of Medicine, Technical University of Munich, Ismaninger Str. 22, 81675 Munich, Germany.
TUM Klinikum · DETechnical University of Munich · DEPhilips (Germany) · DEPhilips (Netherlands) · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTo assess the performance of prospectively accelerated and deep learning (DL) reconstructed T2-weighted (T2w) imaging in volunteers and patients with histologically proven prostate cancer (PCa).

methodsProspectively undersampled T2w datasets were acquired with acceleration factors of 1.7 (reference), 3.4 and 4.8 in 10 healthy volunteers and 23 patients with histologically proven PCa. Image reconstructions using compressed SENSE (C-SENSE) and a combination of C-SENSE and DL-based artificial intelligence (C-SENSE AI) were analyzed. Qualitative image comparison was performed using a 6-point Likert scale (overall image quality, noise, motion artifacts, lesion detection, diagnostic certainty); the T2 and PI-RADS scores were compared between the two reconstructions. Additionally, quantitative image parameters were assessed (apparent SNR, apparent CNR, lesion size, line profiles).

resultsAll C-SENSE AI-reconstructed images received a significantly higher qualitative rating compared to the C-SENSE standard images. Analysis of the quantitative parameters supported this finding, with significantly higher aSNR and aCNR. The line profiles demonstrated a significantly steeper signal change at the border of the prostatic lesion and the adjacent normal tissue in the C-SENSE AI-reconstructed images, whereas the T2 and PI-RADS scores as well as the lesion size did not differ.

conclusionIn this prospective study, we demonstrated the clinical feasibility of a novel C-SENSE AI reconstruction enabling a 58% acceleration in T2w imaging of the prostate while obtaining significantly better image quality.

Indexed as

compressed sensingdeep learningMRIprostate cancer

Identifiers

PMID36497223
PMCPMC9738899
OpenAlexW4309721819

What OpenQuestion holds

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LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.