Evidence map›Paper›PMID 36496987›Full record

ArticleCells2022

Stemness Activity Underlying Whole Brain Regeneration in a Basal Chordate.

Tal Gordon, Tal Zaquin, Mark Alec Kowarsky, Yotam Voskoboynik, Noam Hendin, Omri Wurtzel, Federico Caicci, Lucia Manni, Ayelet Voskoboynik, Noa Shenkar

Open access · goldAbstract read
In one paragraph

Article in Cells, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. Methods for cell isolation and analysis of the highly regenerative tunicateFrontiers in cell and developmental biology · 2023
    Article
  4. Molecular characterization of the immediate wound response of the solitary ascidian Polycarpa mytiligera.Developmental dynamics : an official publication of the American Association of Anatomists · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 6 institutions in 3 countries.

Tal GordonSchool of Zoology, George S. Wise Faculty of Life Sciences, Tel-Aviv University, Tel-Aviv 6997801, Israel.
Tal ZaquinDepartment of Marine Biology, The Leon H. Charney School of Marine Sciences, University of Haifa, Haifa 3498838, Israel.ORCID 0000-0002-3247-3625
Mark Alec KowarskyDepartment of Physics, Stanford University, Stanford, CA 94305, USA.
Yotam VoskoboynikBioinformatics and System Biology, Jacobs School of Engineering, University of California San Diego, San Diego, CA 92093, USA.
Noam HendinSchool of Neurobiology, Biochemistry and Biophysics, George S. Wise Faculty of Life Sciences, Tel-Aviv University, Tel-Aviv 6997801, Israel.
Omri WurtzelSchool of Neurobiology, Biochemistry and Biophysics, George S. Wise Faculty of Life Sciences, Tel-Aviv University, Tel-Aviv 6997801, Israel.
Federico CaicciDepartment of Biology, University of Padova, 35121 Padova, Italy.ORCID 0000-0001-6981-449X
Lucia ManniDepartment of Biology, University of Padova, 35121 Padova, Italy.ORCID 0000-0003-4257-8946
Ayelet VoskoboynikInstitute for Stem Cell Biology and Regenerative Medicine, and Hopkins Marine Station, Stanford University School of Medicine, Stanford, CA 94305, USA.
Noa ShenkarSchool of Zoology, George S. Wise Faculty of Life Sciences, Tel-Aviv University, Tel-Aviv 6997801, Israel.
Tel Aviv University · ILUniversity of Padua · ITChan Zuckerberg Initiative (United States) · USStanford University · USUniversity of California San Diego · USUniversity of Haifa · IL

Funding

Evolutionary Conserved Mechanisms of Neuronal Degeneration and RegenerationR21AG062948 · NIA · STANFORD UNIVERSITY · PI WEISSMAN, IRVING L. · 2020 to 2020
$434k
NIA NIH HHS R21 AG062948
6 · The paper itself

Abstract

Understanding how neurons regenerate following injury remains a central challenge in regenerative medicine. Adult mammals have a very limited ability to regenerate new neurons in the central nervous system (CNS). In contrast, the basal chordate

Indexed as

Brain RegenerationChordataAnimalsBrainCentral Nervous SystemHumansMammalsNeurogenesiscentral nervous systemgene expressionregenerationstem cellstranscriptometunicate

Identifiers

PMID36496987
PMCPMC9738451
OpenAlexW4309721245

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.