ReviewAnimals : an open access journal from MDPI2022
Cryopreservation of Semen in Domestic Animals: A Review of Current Challenges, Applications, and Prospective Strategies.
Review in Animals : an open access journal from MDPI, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 56 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
56 citing papers in PubMed.
- Effect of glycine-enriched freezing medium on post-thaw quality and fertility of Murrah buffalo (Bubalus bubalis) bull semen.Tropical animal health and production · 2026Article
- Effect of Different Equilibration Times in the Freezing Process on Post-Thaw Motility Parameters in Equine Spermatozoa.Reproduction in domestic animals = Zuchthygiene · 2026Article
- Evaluation of sperm kinematics, physical integrity and malondialdehyde levels as indicators of sperm freezability in Pradu Hang Dam chicken.Veterinary research communications · 2026Article
- Comparative Evaluation of TriladylVeterinary sciences · 2026Article
- The effect of zinc selenide nanospheres on porcine semen cryopreservation.Animal bioscience · 2026Article
- Transcriptomics Reveals L-Carnitine to Enhance Semen Quality in Malabari Bucks via Nutrigenomic Regulation of Key Biological Processes Associated With Male Fertility.Reproduction in domestic animals = Zuchthygiene · 2026Article
- Reactive Oxygen Species-Induced Damage in Cryopreserved Bovine Sperm: Mitigation Strategies.Veterinary medicine and science · 2026Review
- Protective Effects of Ginseng Extract Against Oxidative Stress in Chilled Rooster Semen: Implications for Sperm Quality and Fertility.Animals : an open access journal from MDPI · 2026Article
- Effects of Kaempferol Supplementation on the Cryopreservation Quality of Semen from Yuansheng Aite Dairy Rams.Antioxidants (Basel, Switzerland) · 2026Article
- Transgenerational Epigenetic Effect of Cryopreservation of F0 Rooster Sperm (Animals : an open access journal from MDPI · 2026Article
- Dose-dependent effects of Nymphaea lotus extract in semen extenders on sperm quality and fertility in Thai native roosters during cooled and cryopreserved storage.Poultry science · 2026Article
- Holotomography and Multivariate Analysis Reveal Donor-Specific Responses to Antioxidant Supplementation During Stallion Sperm Cryopreservation.Antioxidants (Basel, Switzerland) · 2026Article
- Protective effects of coenzyme Q10-supplemented cryopreservation medium on oxidative stress in frozen canine sperm.Veterinary research communications · 2026Article
- Cryoprotective effects of cholesterol-loaded cyclodextrin and iodixanol on ram sperm: assessment of post-thaw quality and in vitro fertilization outcomes.BMC veterinary research · 2026Article
- Current status and advances in bovine semen production technologies for artificial insemination in Japan.The Journal of reproduction and development · 2026Review
- The Impact of Different Equilibration Methods on the Cryopreservation Effectiveness of Boar Semen.Veterinary medicine and science · 2026Review
- Optimizing South African giraffe Epididymal sperm preservation techniques".Veterinary and animal science · 2026Article
- Proteomic profiling of bull spermatozoa and seminal plasma to inform the rational development of functionally targeted semen extenders for tropical cattle.Veterinary world · 2026Article
- Endocrine-metabolic modulators in sperm biotechnology: cross-species mechanisms and translational priorities.Frontiers in veterinary science · 2026Review
- Research progress on novel bionic cryoprotectants in gamete and embryo cryopreservation.Frontiers in veterinary science · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
Cryopreservation is a way to preserve germplasm with applications in agriculture, biotechnology, and conservation of endangered animals. Cryopreservation has been available for over a century, yet, using current methods, only around 50% of spermatozoa retain their viability after cryopreservation. This loss is associated with damage to different sperm components including the plasma membrane, nucleus, mitochondria, proteins, mRNAs, and microRNAs. To mitigate this damage, conventional strategies use chemical additives that include classical cryoprotectants such as glycerol, as well as antioxidants, fatty acids, sugars, amino acids, and membrane stabilizers. However, clearly current protocols do not prevent all damage. This may be due to the imperfect function of antioxidants and the probable conversion of media components to more toxic forms during cryopreservation.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.