Evidence map›Paper›PMID 36496685›Full record

ArticleFoods (Basel, Switzerland)2022

Modulation of the Gut Microbiota Structure and Function by Two Structurally Different Lemon Pectins.

Jenni Firrman, Karley Mahalak, Jamshed Bobokalonov, LinShu Liu, Jung-Jin Lee, Kyle Bittinger, Lisa M Mattei, Rizalina Gadaingan, Adrienne B Narrowe, Johanna M S Lemons

Open access · goldAbstract read
In one paragraph

Article in Foods (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.8field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 27 citations in OpenAlex.

  1. Review
  2. AnmSystems · 2026
    Article
  3. Review
  4. Article
  5. Article
  6. Foods (Basel, Switzerland) · 2023
    Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Jenni FirrmanUnited States Department of Agriculture, Agriculture Research Service, Eastern Regional Research Center, 600 East Mermaid Lane, Wyndmoor, PA 19462, USA.
Karley MahalakUnited States Department of Agriculture, Agriculture Research Service, Eastern Regional Research Center, 600 East Mermaid Lane, Wyndmoor, PA 19462, USA.
Jamshed BobokalonovUnited States Department of Agriculture, Agriculture Research Service, Eastern Regional Research Center, 600 East Mermaid Lane, Wyndmoor, PA 19462, USA.ORCID 0000-0002-0829-9364
LinShu LiuUnited States Department of Agriculture, Agriculture Research Service, Eastern Regional Research Center, 600 East Mermaid Lane, Wyndmoor, PA 19462, USA.
Jung-Jin LeeChildren's Hospital of Philadelphia, Division of Gastroenterology, Hepatology, and Nutrition, 3401 Civic Center Blvd., Philadelphia, PA 19104, USA.
Kyle BittingerChildren's Hospital of Philadelphia, Division of Gastroenterology, Hepatology, and Nutrition, 3401 Civic Center Blvd., Philadelphia, PA 19104, USA.
Lisa M MatteiChildren's Hospital of Philadelphia, Division of Gastroenterology, Hepatology, and Nutrition, 3401 Civic Center Blvd., Philadelphia, PA 19104, USA.ORCID 0000-0002-2238-0281
Rizalina GadainganUnited States Department of Agriculture, Agriculture Research Service, Eastern Regional Research Center, 600 East Mermaid Lane, Wyndmoor, PA 19462, USA.
Adrienne B NarroweUnited States Department of Agriculture, Agriculture Research Service, Eastern Regional Research Center, 600 East Mermaid Lane, Wyndmoor, PA 19462, USA.
Johanna M S LemonsUnited States Department of Agriculture, Agriculture Research Service, Eastern Regional Research Center, 600 East Mermaid Lane, Wyndmoor, PA 19462, USA.ORCID 0000-0002-5973-5808
United States Department of Agriculture · USChildren's Hospital of Philadelphia · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pectins are plant polysaccharides consumed as part of a diet containing fruits and vegetables. Inside the gastrointestinal tract, pectin cannot be metabolized by the mammalian cells but is fermented by the gut microbiota in the colon with the subsequent release of end products including short-chain fatty acids (SCFA). The prebiotic effects of pectin have been previously evaluated but reports are inconsistent, most likely due to differences in the pectin chemical structure which can vary by molecular weight (MW) and degree of esterification (DE). Here, the effects of two different MW lemon pectins with varying DEs on the gut microbiota of two donors were evaluated in vitro. The results demonstrated that low MW, high DE lemon pectin (LMW-HDE) altered community structure in a donor-dependent manner, whereas high MW, low DE lemon pectin (HMW-LDE) increased taxa within

Indexed as

degree of esterificationgut microbiotaLachnospiraceaelemon pectinmolecular weightpectinshort-chain fatty acids

Identifiers

PMID36496685
PMCPMC9739951
OpenAlexW4311050702

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.