Evidence map›Paper›PMID 36496617›Full record

ArticleFoods (Basel, Switzerland)2022

Establishment of a Sonotrode Ultrasound-Assisted Extraction of Phenolic Compounds from Apple Pomace.

María Del Carmen Razola-Díaz, María José Aznar-Ramos, Eduardo Jesús Guerra-Hernández, Belén García-Villanova, Ana María Gómez-Caravaca, Vito Verardo

Open access · goldAbstract read
In one paragraph

Article in Foods (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 26 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

María Del Carmen Razola-DíazDepartment of Nutrition and Food Science, Campus of Cartuja, University of Granada, 18011 Granada, Spain.ORCID 0000-0002-0611-9139
María José Aznar-RamosDepartment of Nutrition and Food Science, Campus of Cartuja, University of Granada, 18011 Granada, Spain.ORCID 0000-0003-1283-0717
Eduardo Jesús Guerra-HernándezDepartment of Nutrition and Food Science, Campus of Cartuja, University of Granada, 18011 Granada, Spain.ORCID 0000-0002-2841-7743
Belén García-VillanovaDepartment of Nutrition and Food Science, Campus of Cartuja, University of Granada, 18011 Granada, Spain.ORCID 0000-0001-5114-300X
Ana María Gómez-CaravacaInstitute of Nutrition and Food Technology 'José Mataix', Biomedical Research Centre, University of Granada, Avda del Conocimiento sn., 18100 Armilla, Spain.
Vito VerardoDepartment of Nutrition and Food Science, Campus of Cartuja, University of Granada, 18011 Granada, Spain.ORCID 0000-0003-0723-5163
Universidad de Granada · ES

Funding

European Union's Horizon 2020 research and innovation program 817936
6 · The paper itself

Abstract

Apple pomace is the main by-product from apple processing in the juice industry and is considered a source of polyphenols with several health bioactivities. Thus, this research focuses on the establishment of the ultrasound-assisted extraction of total phenolic compounds, focusing on phloretin and phloridzin, with high antioxidant activity from apple pomace, using a sonotrode. We used a Box-Behnken design of 15 experiments with 3 independent factors (ethanol (%), time (min) and amplitude (%)). The responses evaluated were the sum of phenolic compounds, phloretin and phloridzin measured by HPLC-MS-ESI-TOF, and antioxidant activity measured by DPPH, ABTS and FRAP. The validity of the model was confirmed by ANOVA. Further, it was carried out using a comparison between different apple pomaces with or without seeds extracted by the optimal conditions. Phloretin and phloridzin accounted for 7 to 32% of the total phenolic compounds in the apple pomaces. Among all the apple pomace analyzed, that of the variety Gala had the highest phenolic content and antioxidant activity. The presence of the cyanogenic compound amygdalin was detected in apple pomaces that contained seeds accompanied with a higher content of phloretin and phloridzin but a lower content of flavan-3-ols.

Indexed as

amygdalinantioxidant activityby-productHPLC–MSMaluswaste revalorization

Identifiers

PMID36496617
PMCPMC9740410
OpenAlexW4310187265

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.