Evidence map›Paper›PMID 36495757›Full record

ArticleJournal of psychosomatic research2023

Psychological factors associated with reporting side effects following COVID-19 vaccination: A prospective cohort study (CoVAccS - Wave 3).

Louise E Smith, Julius Sim, Susan M Sherman, Richard Amlôt, Megan Cutts, Hannah Dasch, Nick Sevdalis, G James Rubin

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of psychosomatic research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 6 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Louise E SmithDepartment of Psychological Medicine, Institute of Psychiatry, Psychology and Neuroscience, Weston Education Centre, King's College London, London SE5 9RJ, UK; NIHR Health Protection Research Unit in Emergency Preparedness and Response, Weston Education Centre, King's College London, London SE5 9RJ, UK. Electronic address: louise.e.smith@kcl.ac.uk.
Julius SimSchool of Medicine, David Weatherall Building, University Road, Keele University, Staffordshire, ST5 5BG, UK.
Susan M ShermanSchool of Psychology, Dorothy Hodgkin Building, Keele University, Staffordshire, ST5 5BG, UK.
Richard AmlôtNIHR Health Protection Research Unit in Emergency Preparedness and Response, Weston Education Centre, King's College London, London SE5 9RJ, UK; UK Health Security Agency, Chief Scientific Officer's Group, 17 Smith Square, London, SW1P 3HX, UK.
Megan CuttsSchool of Psychology, Dorothy Hodgkin Building, Keele University, Staffordshire, ST5 5BG, UK.
Hannah DaschCentre for Implementation Science, NIHR ARC South London, King's College London, Institute of Psychiatry, Psychology & Neuroscience, De Crespigny Park, London SE5 8AF, UK.
Nick SevdalisCentre for Implementation Science, NIHR ARC South London, King's College London, Institute of Psychiatry, Psychology & Neuroscience, De Crespigny Park, London SE5 8AF, UK.
G James RubinDepartment of Psychological Medicine, Institute of Psychiatry, Psychology and Neuroscience, Weston Education Centre, King's College London, London SE5 9RJ, UK; NIHR Health Protection Research Unit in Emergency Preparedness and Response, Weston Education Centre, King's College London, London SE5 9RJ, UK.
King's College London · GBKeele University · GBUK Health Security Agency

Funding

Department of Health
6 · The paper itself

Abstract

objectiveTo investigate symptom reporting following the first and second COVID-19 vaccine doses, attribution of symptoms to the vaccine, and factors associated with symptom reporting.

methodsProspective cohort study (T1: 13-15 January 2021, T2: 4-15 October 2021). Participants were aged 18 years or older, living in the UK. Personal, clinical, and psychological factors were investigated at T1. Symptoms were reported at T2. We used logistic regression analyses to investigate associations.

resultsAfter the first COVID-19 vaccine dose, 74.1% (95% CI 71.4% to 76.7%, n = 762/1028) of participants reported at least one injection-site symptom, while 65.0% (95% CI 62.0% to 67.9%, n = 669/1029) reported at least one other (non-injection-site) symptom. Symptom reporting was associated with being a woman and younger. After the second dose, 52.9% (95% CI 49.8% to 56.0%, n = 532/1005) of participants reported at least one injection-site symptom and 43.7% (95% CI 40.7% to 46.8%, n = 440/1006) reported at least one other (non-injection-site) symptom. Symptom reporting was associated with having reported symptoms after the first dose, having an illness that put one at higher risk of COVID-19 (non-injection-site symptoms only), and not believing that one had enough information about COVID-19 to make an informed decision about vaccination (injection-site symptoms only).

conclusionsWomen and younger people were more likely to report symptoms from vaccination. People who had reported symptoms from previous doses were also more likely to report symptoms subsequently, although symptom reporting following the second vaccine was lower than following the first vaccine. Few psychological factors were associated with symptom reporting.

Indexed as

COVID-19COVID-19 VaccinesDrug-Related Side Effects and Adverse ReactionsFemaleHumansProspective StudiesVaccinationCOVID-19 VaccinesAdverse effectsCOVID-19ImmunizationPsychological factorsSymptom perception

Identifiers

PMID36495757
PMCPMC9708101
OpenAlexW4311986543

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.