Evidence map›Paper›PMID 36495306›Full record

ArticleThe Laryngoscope2023

Joint Vestibular Schwannoma Enlargement Prediction and Segmentation Using a Deep Multi-task Model.

Kai Wang, Nicholas A George-Jones, Liyuan Chen, Jacob B Hunter, Jing Wang

Abstract read
In one paragraph

Article in The Laryngoscope, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 4 syntheses or guidelines pooled it.

  1. Pooled it
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  4. The impact of artificial intelligence in the diagnosis and management of acoustic neuroma: A systematic review.Technology and health care : official journal of the European Society for Engineering and Medicine · 2024
    Pooled it
  5. Turing problems in otolaryngology: a scoping review of the principal challenges of artificial ıntelligence and large language models.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2026
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  14. Vision Transformer-Based Multilabel Survival Prediction for Oropharynx Cancer After Radiation Therapy.International journal of radiation oncology, biology, physics · 2024
    Article
  15. Applications and Integration of Radiomics for Skull Base Oncology.Advances in experimental medicine and biology · 2024
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Kai WangThe Department of Radiation Oncology, University of Texas Southwestern Medical Center, Dallas, Texas, USA.ORCID 0000-0003-2155-1445
Nicholas A George-JonesThe Department of Otolaryngology-Head and Neck Surgery, University of Texas Southwestern Medical Center, Dallas, Texas, USA.
Liyuan ChenThe Department of Radiation Oncology, University of Texas Southwestern Medical Center, Dallas, Texas, USA.
Jacob B HunterThe Department of Otolaryngology-Head and Neck Surgery, University of Texas Southwestern Medical Center, Dallas, Texas, USA.ORCID 0000-0003-3479-1309
Jing WangThe Department of Radiation Oncology, University of Texas Southwestern Medical Center, Dallas, Texas, USA.

Funding

Research Training Program in OtolaryngologyT32DC000040 · NIDCD · UNIVERSITY OF IOWA · PI HANSEN, MARLAN R · 1993 to 2025
$5.4M
NIDCD NIH HHS T32 DC000040
6 · The paper itself

Abstract

objectiveTo develop a deep-learning-based multi-task (DMT) model for joint tumor enlargement prediction (TEP) and automatic tumor segmentation (TS) for vestibular schwannoma (VS) patients using their initial diagnostic contrast-enhanced T1-weighted (ceT1) magnetic resonance images (MRIs).

methodsInitial ceT1 MRIs for VS patients meeting the inclusion/exclusion criteria of this study were retrospectively collected. VSs on the initial MRIs and their first follow-up scans were manually contoured. Tumor volume and enlargement ratio were measured based on expert contours. A DMT model was constructed for jointly TS and TEP. The manually segmented VS volume on the initial scan and the tumor enlargement label (≥20% volumetric growth) were used as the ground truth for training and evaluating the TS and TEP modules, respectively.

resultsWe performed 5-fold cross-validation with the eligible patients (n = 103). Median segmentation dice coefficient, prediction sensitivity, specificity, accuracy, and area under the receiver operating characteristic curve (AUC) were measured and achieved the following values: 84.20%, 0.68, 0.78, 0.72, and 0.77, respectively. The segmentation result is significantly better than the separate TS network (dice coefficient of 83.13%, p = 0.03) and marginally lower than the state-of-the-art segmentation model nnU-Net (dice coefficient of 86.45%, p = 0.16). The TEP performance is significantly better than the single-task prediction model (AUC = 0.60, p = 0.01) and marginally better than a radiomics-based prediction model (AUC = 0.70, p = 0.17).

conclusionThe proposed DMT model is of higher learning efficiency and achieves promising performance on TEP and TS. The proposed technology has the potential to improve VS patient management. LEVEL OF EVIDENCE: NA Laryngoscope, 133:2754-2760, 2023.

Indexed as

Image Processing, Computer-AssistedNeuroma, AcousticHumansMagnetic Resonance ImagingRetrospective Studiesdeep learningimage segmentationmulti-task learningtumor enlargement predictionvestibular schwannoma

Identifiers

PMID36495306
PMCPMC10256836

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.