ArticleEuropean journal of applied physiology2023
Fatigue-induced changes in hamstrings' active muscle stiffness: effect of contraction type and implications for strain injuries.
Article in European journal of applied physiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07395583 (Efficacy of Eccentric Over Concentric Hamstring Exercises in Elite Male Footballers for Preventing Non-Contact Hamstring Injuries), which is not on this map. Cited by 13 papers, 1 of them a synthesis that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Efficacy of Eccentric Over Concentric Hamstring Exercises in Elite Male Footballers for Preventing Non-Contact Hamstring Injuries: A Randomized Controlled Trial
Who cites it
13 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Mechanisms of hamstring strain injuries in sprinting: an integrative scoping review of intrinsic, biomechanical and modifiable risk factors.Frontiers in physiology · 2026Pooled it
- Trial
- The effects of Four-Week plyometric training on delaying muscle fatigue in youth rowers.Scientific reports · 2025Trial
- Intra- and intermuscular shear wave speed distributions in the human hamstrings during isometric and eccentric contractions.European journal of applied physiology · 2026Article
- Skeletal muscle overuse injury: pathophysiological mechanisms, molecular pathways, and rehabilitation strategies.Frontiers in physiology · 2026Review
- Effects of resistance exercises on rotator cuff muscle mechanical characteristics in shoulders with and without rotator cuff tears.PloS one · 2026Article
- Variability of the Sprint Step Movement Pattern and Its Association with Hamstring Injury Risk.Journal of clinical medicine · 2025Article
- Acute Effects of Nordic Hamstring Exercise on Hamstring Stiffness: A Randomised Controlled Trial.Journal of clinical medicine · 2025Article
- Muscle fatigue assessment using surface electromyography in farm operations performed in protected cultivation.Scientific reports · 2025Article
- Maximal isometric and eccentric hamstring strength is influenced by body mass and additional load: Does the critical point at which peak knee flexor force is achieved play a role?Frontiers in physiology · 2025Article
- Changes in hamstrings' active stiffness during fatigue tasks are modulated by contraction duration rather than intensity.Scientific reports · 2024Article
- Assessment of Muscle Stiffness Using the MyotonPro: Effects of Fatigue on Vastus Lateralis and Medialis Muscles.Journal of personalized medicine · 2024Article
- Acute fatigue-induced alterations in hamstring muscle properties after repeated Nordic hamstring exercises.Science progressArticle
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
purposeHamstring strain injuries may occur due to differential fatigue and compromised mechanical properties among the hamstring muscles. We examined (1) the effect of fatigue on hamstrings active muscle stiffness, and (2) whether contraction type affects active muscle stiffness changes during a submaximal fatiguing task.
methodsNine healthy males completed 99 submaximal knee flexions in isometric (ISO), concentric (CON), and eccentric (ECC) conditions. We measured the knee flexor maximal voluntary torque (MVT) (pre/post), shear wave velocity (SWV) during contraction and transverse relaxation times (T2) (pre/post) in biceps femoris long head (BFlh), semitendinosus (ST), and semimembranosus (SM) muscles.
resultsMVT decreased substantially after all conditions (- 18.4 to - 33.6%). The average relative torque sustained during the task was lower in CON than ISO and ECC, but absolute torque was similar. SWV interindividual responses were highly variable across muscles and contraction types. On average, BFlh SWV tended to increase in ISO (0.4 m/s, 4.5%, p = 0.064) but decreased in ECC condition (- 0.8 m/s, - 7.7%, p < 0.01). ST SWV decreased in CON (- 1.1 m/s, - 9.0%, p < 0.01), while it remained unchanged in ISO and ECC. SM SWV decreased in CON (- 0.8 m/s, - 8.1%, p < 0.01), but it was unaffected in ISO and variable in ECC.
conclusionFatigue has a differential effect on the mechanical properties of the constituent hamstring muscles, as measured with shear wave elastography, depending upon contraction type. We found preliminary evidence that BFlh is more fatigued than ST or SM during eccentric contractions, which may explain its susceptibility to strain injuries.
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