Evidence map›Paper›PMID 36493682›Full record

Observational studyClinical imaging2023

Access to cardiac PET/CT by sarcoidosis patients and cost-effectiveness analysis of cardiac PET/MR compared to the standard of care.

Kritika Subramanian, Juana Martinez, Joseph R Osborne, Sean Nicholson, Jessica Van Parys, Parmanand Singh, Anjile An, Rachel Heise, Tamara Al-Hakim, Mindy Buchanan and 1 more

Abstract readObservational Study
In one paragraph

Observational study in Clinical imaging, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Kritika SubramanianDivision of Molecular Imaging & Therapeutics, Department of Radiology, Weill Cornell Medicine, New York, NY, United States of America. Electronic address: krs9089@nyp.org.
Juana MartinezDivision of Molecular Imaging & Therapeutics, Department of Radiology, Weill Cornell Medicine, New York, NY, United States of America.
Joseph R OsborneDivision of Molecular Imaging & Therapeutics, Department of Radiology, Weill Cornell Medicine, New York, NY, United States of America.
Sean NicholsonDepartment of Policy Analysis and Management, Sloan, Cornell Institute for Public Affairs, New York, NY, United States of America.
Jessica Van ParysDepartment of Economics, Hunter College, City University of New York, New York, NY, United States of America.
Parmanand SinghDepartment of Cardiology, Weill Cornell Medicine, New York, NY, United States of America.
Anjile AnDepartment of Population Health Sciences, Weill Cornell Medicine, New York, NY, United States of America.
Rachel HeiseDepartment of Population Health Sciences, Weill Cornell Medicine, New York, NY, United States of America.
Tamara Al-HakimFoundation for Sarcoidosis Research, Chicago, IL, United States of America.
Mindy BuchananFoundation for Sarcoidosis Research, Chicago, IL, United States of America.
Trisha YounDivision of Molecular Imaging & Therapeutics, Department of Radiology, Weill Cornell Medicine, New York, NY, United States of America.

Funding

Clinical and Translational Science AwardUL1TR001873 · NCATS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI REILLY, MUREDACH P · 2016 to 2025
$99.0M
Disparities in COVID Disease Severity and Outcomes in New York CityUL1TR002384 · NCATS · WEILL MEDICAL COLL OF CORNELL UNIV · PI JULIANNE L IMPERATO-MCGINLEY · 2017 to 2026
$86.2M
PLANNING GRANT FOR THE INSTITUTIONAL CLINICAL AND TRANSLATIONAL SCIENCE AWARDP20RR023503 · NCRR · WEILL MEDICAL COLL OF CORNELL UNIV · PI IMPERATO-MCGINLEY, JULIANNE L · 2006 to 2006
$252k
NCATS NIH HHS UL1 TR001873NCATS NIH HHS UL1 TR002384NCRR NIH HHS P20 RR023503
6 · The paper itself

Abstract

importanceCardiac sarcoidosis is associated with a high mortality rate. Given multiple barriers to obtaining cardiac PET imaging, we suspect individuals with access to this imaging modality are not representative of the Sarcoid patient population, which in the United States are predominantly Black females.

objectiveTo evaluate the demographics of patients with cardiac PET access and the cost-effectiveness of cardiac PET/MR imaging relative to standard of care.

designThis is a retrospective, observational study. The demographic information of patients with suspected cardiac sarcoidosis and cardiac PET/CT imaging within a national registry of sarcoidosis were reviewed (n = 4561). An individual-level, continuous, time-state transition model was used for the evaluation of long-term cost-effectiveness for the combined cardiac PET/MR compared to standard of care cardiac MR followed by cardiac PET/CT.

resultsPatients who underwent cardiac PET in the national registry had 88.35% higher odds of being male (p < 0.001) and 43.82% higher odds of being White (p = 0.003) than their counterparts who did not have cardiac PET imaging. Combined cardiac PET/MR had overall lower total lifetime costs ($8761 vs $10,777) and overall improved expected quality of life-years compared to the standard of care (0.77 vs 0.69). CONCLUSION AND RELEVANCE: The findings suggest that patients with access to cardiac PET/CT are not representative of the patient population most likely to have cardiac sarcoidosis in this limited study evaluation. Universal insurance coverage should be considered for Cardiac PET imaging as same day cardiac PET and MR imaging has potential long-term cost and quality of life benefit.

Indexed as

Positron Emission Tomography Computed TomographySarcoidosisCost-Effectiveness AnalysisFemaleFluorodeoxyglucose F18HumansMagnetic Resonance ImagingMalePositron-Emission TomographyQuality of LifeStandard of CareFluorodeoxyglucose F18Cardiac PET/MRCardiac sarcoidosisCost-effectiveness analysisHealth care equitySarcoidosis

Identifiers

PMID36493682
PMCPMC9812891

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.