Evidence map›Paper›PMID 36493610›Full record

ArticleEnvironment international2023

Contributions of nearby agricultural insecticide applications to indoor residential exposures.

Jessica M Madrigal, Robert B Gunier, Rena R Jones, Abigail Flory, Catherine Metayer, John R Nuckols, Mary H Ward

Open access · goldAbstract read
In one paragraph

Article in Environment international, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
4.4field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 25 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 6 institutions in 1 country.

Jessica M MadrigalOccupational and Environmental Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Rockville, MD, USA. Electronic address: jessica.madrigal@nih.gov.
Robert B GunierCenter for Environmental Research and Community Health (CERCH), University of California, Berkeley, School of Public Health, Berkeley, CA, USA.
Rena R JonesOccupational and Environmental Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Rockville, MD, USA.
Abigail FloryWestat Inc, Rockville, MD, USA.
Catherine MetayerUniversity of California, Berkeley, School of Public Health, Berkeley, CA, USA.
John R NuckolsDepartment of Environmental and Radiological Health Sciences, Colorado State University, Fort Collins, CO, USA; JRN Environmental Health Sciences, Ltd, North Bethesda, MD, USA.
Mary H WardOccupational and Environmental Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Rockville, MD, USA.
National Cancer Institute · USBerkeley Public Health Division · USColorado State University · USNational Institutes of Health · USUniversity of California, Berkeley · USWestat (United States) · US

Funding

Training CoreP42ES004705 · NIEHS · UNIVERSITY OF CALIFORNIA BERKELEY · PI MCHALE, CLIONA · 1987 to 2025
$74.6M
Cancer Risk and Environmental ExposuresZIACP010125 · NCI · DIVISION OF CANCER EPIDEMIOLOGY AND GENETICS · PI PURDUE, MARK · 2009 to 2025
$41.3M
Environmental and Molecular Epidemiology of Childhood LeukemiaR01ES009137 · NIEHS · UNIVERSITY OF CALIFORNIA BERKELEY · PI METAYER, CATHERINE · 1999 to 2013
$21.1M
Support For Infrastructure of Childhood Leukemia Environmental ResearchR24ES028524 · NIEHS · UNIVERSITY OF CALIFORNIA BERKELEY · PI Robert Gunier · 2017 to 2026
$2.3M
Geographic-based exposure assessment of agricultural ch*R01CA092683 · NCI · COLORADO STATE UNIVERSITY-FORT COLLINS · PI NUCKOLS, JOHN R · 2001 to 2004
$949k
EPA R836159C003Intramural NIH HHS Z99 CA999999Intramural NIH HHS ZIA CP010125NCI NIH HHS N02 CP011015NCI NIH HHS R01 CA092683NIEHS NIH HHS P42 ES004705NIEHS NIH HHS R01 ES009137NIEHS NIH HHS R24 ES028524
6 · The paper itself

Abstract

backgroundPesticide exposure has been associated with adverse health effects. We evaluated relationships between proximity to agricultural insecticide applications and insecticides in household dust, accounting for land use and wind direction.

methodsWe measured concentrations (ng/g) of nine insecticides in carpet-dust samples collected from 598 California homes. Using a geographic information system (GIS), we integrated the California Pesticide Use Reporting (CPUR) database to estimate agricultural use within residential buffers with radii of 0.5 to 4 km. We calculated the density of use (kg/km

resultsChlorpyrifos use within 1-4 km was associated with 1 to 2-times higher dust concentrations in both the 60- and 365-day periods. Carbaryl applications within 2-4 km of homes 60-days prior to dust collection were associated with 3 to 7-times higher concentrations and the 4 km trend was strongest using the wind-adjusted metric (p-trend = 0.04). For diazinon, there were 2-times higher concentrations for the 60-day metrics in the 2 km buffer and for the CPUR and wind-adjusted metrics within 4 km. Cyfluthrin, phosmet, and azinphos-methyl applications within 4 km in the prior 365-days were associated with 2-, 6-, and 3-fold higher odds of detection, respectively.

conclusionsAgricultural use of six of the nine insecticides within 4 km is an important determinant of indoor contamination. Our findings demonstrated that GIS-based metrics for quantifying potential exposure to fugitive emissions from agriculture should incorporate tailored distances and time periods and support wind-adjustment for some, but not all insecticides.

Indexed as

ChlorpyrifosInsecticidesPesticidesPhosmetAgricultureAzinphosmethylCarbarylDiazinonDustEnvironmental ExposureNitrilesPyrethrinsAzinphosmethylCarbarylChlorpyrifoscyfluthrinDiazinonDustInsecticidesNitrilesPesticidesPhosmetPyrethrinsEnvironmental epidemiology, Dust, AgricultureExposure assessmentInsecticidesPesticides

Identifiers

PMID36493610
PMCPMC10038187
OpenAlexW4309860037

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.