Evidence map›Paper›PMID 36487186›Full record

ArticleAmerican journal of physiology. Heart and circulatory physiology2023

Sex still matters in cardiovascular research.

Merry L Lindsey, Jason R Carter, Crystal M Ripplinger, Zamaneh Kassiri, Kara Hansell Keehan, Keith R Brunt, Jonathan A Kirk, Petra Kleinbongard, Amanda J LeBlanc

Abstract readEditorial
In one paragraph

Article in American journal of physiology. Heart and circulatory physiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Article
  2. Assessing health in aging male and female mice: does cardiac function dictate frailty or physical resilience?The journals of gerontology. Series A, Biological sciences and medical sciences · 2026
    Article
  3. Progress on incorporating sex as a biological variable in cardiovascular research.American journal of physiology. Heart and circulatory physiology · 2025
    Article
  4. What frozen human hearts can tell us about treating heart failure.American journal of physiology. Heart and circulatory physiology · 2025
    Article
  5. Article
  6. Hypertension-induced heart failure disrupts cardiac sympathetic innervation.American journal of physiology. Heart and circulatory physiology · 2024
    Article
  7. Sex as a biological variable for cardiovascular physiology.American journal of physiology. Heart and circulatory physiology · 2024
    Review
  8. Article
  9. A review of the historical use of sex as a biological variable in theAmerican journal of physiology. Heart and circulatory physiology · 2023
    Review
  10. Autonomic cardiovascular control during exercise.American journal of physiology. Heart and circulatory physiology · 2023
    Review
  11. Article
  12. Review
  13. Spring cleaning: freshening up the portfolio.American journal of physiology. Heart and circulatory physiology · 2023
    Article
  14. We asked and you answered.American journal of physiology. Heart and circulatory physiology · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Merry L LindseySchool of Graduate Studies and Research, Meharry Medical College, Nashville, Tennessee.ORCID 0000-0002-4090-0391
Jason R CarterRobbins College of Health and Human Sciences, Baylor University, Waco, Texas.ORCID 0000-0001-7350-6537
Crystal M RipplingerDepartment of Pharmacology, UC Davis School of Medicine, Davis, California.ORCID 0000-0002-9908-4106
Zamaneh KassiriDepartment of Physiology, Cardiovascular Research Center, University of Alberta, Edmonton, Alberta, Canada.ORCID 0000-0002-9357-0912
Kara Hansell KeehanAssociate Publications Director, Editorial and Content Development and Executive Editor, AJP-Heart and Circulatory Physiology, American Physiological Society, Rockville, Maryland.
Keith R BruntFaculty of Medicine, Department of Pharmacology, Dalhousie University, Saint John, New Brunswick, Canada.ORCID 0000-0002-5728-8135
Jonathan A KirkDepartment of Cell and Molecular Physiology, Loyola University Chicago Stritch School of Medicine, Chicago, Illinois.ORCID 0000-0002-5192-2860
Petra KleinbongardInstitute for Pathophysiology, West German Heart and Vascular Center, University of Essen Medical School, Essen, Germany.ORCID 0000-0003-3576-3772
Amanda J LeBlancDepartment of Cardiovascular and Thoracic Surgery, School of Medicine and Cardiovascular Innovation Institute, University of Louisville, Louisville, Kentucky.ORCID 0000-0003-2507-1203

Funding

Project 3 (Mercola)P01HL141084 · NHLBI · STANFORD UNIVERSITY · PI Joseph C. Wu · 2019 to 2026
$21.1M
The Role of Adrenergic Stimulation in ArrhythmogenesisR01HL111600 · NHLBI · UNIVERSITY OF CALIFORNIA-IRVINE · PI Crystal May Ripplinger · 2012 to 2026
$7.1M
GSK-3β Localizes to the Myofilament and Modifies its Function in Ischemic CardiomyopathyR01HL136737 · NHLBI · UNIVERSITY OF CHICAGO · PI JONATHAN A KIRK · 2017 to 2026
$4.5M
Alcohol and Neurovascular Control in HumansR01AA024892 · NIAAA · MONTANA STATE UNIVERSITY - BOZEMAN · PI CARTER, JASON R · 2017 to 2021
$1.8M
NHLBI NIH HHS P01 HL141084NHLBI NIH HHS R01 HL111600NHLBI NIH HHS R01 HL136737NIAAA NIH HHS R01 AA024892
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Biomedical ResearchCardiovascular SystemHeartReproducibility of ResultsResearch DesignVisceracardiaccardiovasculareditorialreproducibilityrigorrigor and reproducibilitysex

Identifiers

PMID36487186
PMCPMC9799132

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.