Evidence map›Paper›PMID 36486180›Full record

ReviewCanadian Urological Association journal = Journal de l'Association des urologues du Canada2023

Use of timed alarm device for pediatric daytime urinary incontinence Meta-analysis of comparative studies.

Michael E Chua, Mandy Rickard, Jin Kyu Kim, Natasha Brownrigg, Joana Dos Santos, Luzelle Kate Aba, Armando Lorenzo, Niraj Mistry

Open access · diamondAbstract readReview
In one paragraph

Review in Canadian Urological Association journal = Journal de l'Association des urologues du Canada, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 72% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 0 citations in OpenAlex.

  1. Trial
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Michael E ChuaGlobal Surgery, Department of Surgery, University of Toronto, Toronto, ON, Canada.
Mandy RickardDivision of Urology, Department of Surgery, The Hospital for Sick Children, Toronto, ON, Canada.
Jin Kyu KimTemerty Faculty of Medicine, University of Toronto, Toronto, ON, Canada.
Natasha BrownriggDivision of Urology, Department of Surgery, The Hospital for Sick Children, Toronto, ON, Canada.
Joana Dos SantosDivision of Urology, Department of Surgery, The Hospital for Sick Children, Toronto, ON, Canada.
Luzelle Kate AbaInstitute of Urology, St. Luke's Medical Center, Quezon City, NCR, Philippines.
Armando LorenzoDivision of Urology, Department of Surgery, The Hospital for Sick Children, Toronto, ON, Canada.
Niraj MistryDepartment of Pediatrics, The Hospital for Sick Children, Toronto, ON, Canada.
Hospital for Sick Children · CAUniversity of Toronto · CASt. Luke's Medical Center · PH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThis meta-analysis aimed to determine the comparative effectiveness of timed alarm device-assisted urotherapy vs. standard urotherapy alone in managing pediatric daytime urinary incontinence (pDUI).

methodsA systematic literature search was performed in December 2021, with an update search in July 2022. Comparative studies assessing the pDUI treatment effectiveness of timed alarm device-assisted urotherapy vs. urotherapy alone were identified and evaluated according to Cochrane collaboration recommendations. The assessed outcome includes pDUI complete response and adherence rates. Relative risk (RR ) with 95% confidence intervals (CI) was extrapolated. A random-effects model was used to pool effect estimates. Heterogeneity was assessed with sensitivity and subgroup analysis performed according to study design and comparative group characteristics. GRADE criteria were used to assess evidence certainty. (PROSPEROCRD 42022299173).

resultsFour studies (three randomized controlled trials [RCTs] and one retrospective cohort) with 635 cases were included. The pooled effect estimates of pDUI complete response showed no differences between intervention groups (RR 1.20, 95% CI 0.81, 1.76). Pooled effect estimates for treatment adherence were generated from two studies, which showed significantly better adherence for the timed-alarm device group (RR 2.97, 95% CI 1.46, 6.06). Significant interstudy heterogeneity was noted; the source is likely from the study design and comparator device characteristics. The quality of evidence was assessed to be of very low certainty.

conclusionsBased on very low certainty evidence, timed alarm device-assisted urotherapy does not seem to have the advantage of complete treatment response over standard urotherapy alone in managing pDUI; however, a timed-alarm device is likely able to improve urotherapy treatment adherence.

Identifiers

PMID36486180
PMCPMC10073526
OpenAlexW4310958175

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.