Evidence map›Paper›PMID 36486175›Full record

ArticleCanadian Urological Association journal = Journal de l'Association des urologues du Canada2023

Assessment of the epidemiological trends for prostate cancer using administrative data in Ontario.

Fred Saad, Bimal Bhindi, Krista Noonan, Michael Ong, Kimberly Castellano, Alexandra Kourkounakis, Christopher J D Wallis

Open access · diamondAbstract read
In one paragraph

Article in Canadian Urological Association journal = Journal de l'Association des urologues du Canada, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 2 citations in OpenAlex.

  1. Observational
  2. Article
  3. Navigating the screening and treatment of prostate cancer.Canadian Urological Association journal = Journal de l'Association des urologues du Canada · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 6 institutions in 3 countries.

Fred SaadCentre Hospitalier de l'Université de Montréal, Montreal, QC, Canada.
Bimal BhindiSection of Urology, Department of Surgery, University of Calgary, Calgary, AB, Canada.
Krista NoonanBC Cancer-Surrey, University of British Columbia, Vancouver, BC, Canada.
Michael OngThe Ottawa Hospital, University of Ottawa, Ottawa, ON, Canada.
Kimberly CastellanoJanssen Inc., Toronto, ON, Canada.
Alexandra KourkounakisJanssen Inc., Toronto, ON, Canada.
Christopher J D WallisDepartment of Urology, Vanderbilt University Medical Center, Nashville, TN, United States & Division of Urology, Department of Surgery, Mount Sinai Hospital & University of Toronto, Toronto, ON, Canada.
Janssen (Switzerland) · CHCentre Hospitalier de l’Université de Montréal · CAMount Sinai Hospital · CAUniversity of British Columbia · CAUniversity of Calgary · CAVanderbilt University Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionStudies have shown fluctuations in prostate cancer (PCa) incidence and prevalence over time and by region. Less is known about the most recent epidemiological trends by PCa disease stage.

methodsThis study was a population-based, sequential, cross-sectional analysis that used administrative health data from Ontario, Canada. After inclusion, patients were classified into non-metastatic (nm) PCa and metastatic (m) PCa. The primary study outcome was a description of temporal trends in the incidence and prevalence of PCa over the study period (2010-2019), stratified by disease state. Crude incidence and prevalence rates were estimated for each year in the study period.

resultsOverall, there were 131 718 men living with PCa in 2019. The incident cohort contained 86 123 patients with nmPCa (n=65 691, 76.3%), mPCa (n=8431, 9.8%), or unknown stage (n=12 001, 13.9%). The prevalence increased from 216 to 253 per 10 000 men between 2010 and 2019, respectively. Between 2011 and 2014, overall PCa incidence decreased from 20.9 to 15.4 per 10 000 men, followed by an increase to 18.8 per 10 000 in 2018. The nmPCa incidence rate was considerably higher compared with mPCa and followed a trend similar to the overall incidence. In contrast, the incidence rate for mPCa demonstrated a continuous increase from 1.5 per 10 000 in 2010 to 2.4 per 10 000 in 2018.

conclusionsThe overall prevalence of PCa has risen steadily over the last decade, despite fluctuations in nmPCa incidence. The concurrent rise in mPCa and nmPCa requires further study regarding the burden of localized and systemic treatment.

Identifiers

PMID36486175
PMCPMC10073519
OpenAlexW4310938580

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.