ReviewReviews in endocrine & metabolic disorders2023
Diagnostic and prognostic utility of phase angle in patients with cancer.
Review in Reviews in endocrine & metabolic disorders, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
25 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Bioelectrical impedance analysis-derived phase angle (PhA) in lung cancer patients: a systematic review.BMC cancer · 2024Pooled it
- Observational
- Phase angle as a prognostic nutritional marker for survival in nasopharyngeal carcinoma patients undergoing chemoradiotherapy: a prospective cohort study.Frontiers in nutrition · 2026Article
- Novel insights into phase angle in breast cancer - stage-specific associations between body composition and metabolic age.Reports of practical oncology and radiotherapy : journal of Greatpoland Cancer Center in Poznan and Polish Society of Radiation Oncology · 2026Article
- Bioelectrical impedance-derived phase angle as a contextual indicator for steatotic liver disease and hepatic fat estimation.Frontiers in nutrition · 2026Article
- Body water distribution, early malnutrition and sarcopenia in ADPKD: insights from a cross sectional study.Journal of nephrology · 2025Article
- Article
- Effect of a 12-week exercise program on phase angle in women with breast cancer.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025Article
- Phase angle as a prognostic biomarker in metastatic colorectal cancer: A prospective trial.World journal of gastrointestinal oncology · 2025Article
- Stronger associations of the phase angle than the TyG index with micro- and macrovascular complications in patients with type 2 diabetes.Lipids in health and disease · 2025Article
- Application progress of early nutrition intervention in patients with hepatocellular carcinoma after liver transplantation.World journal of gastrointestinal surgery · 2025Review
- Article
- Sarcopenia in Terminally Ill Patients with Cancer: Clinical Implications, Diagnostic Challenges, and Management Strategies.Journal of hospice and palliative care · 2025Review
- Association between phase angle and all-cause mortality in adults aged 18-49 years: NHANES 1999-2004.Scientific reports · 2025Article
- Predictive classification and regression models for bioimpedance vector analysis: Insights from a southern Cuban cohort.Journal of electrical bioimpedance · 2025Article
- Phase angle as a predictor of prolonged length of hospital stay and adverse outcomes in elderly medical inpatients: a retrospective cohort study.Frontiers in nutrition · 2025Article
- Bioimpedance-derived body composition parameters predict mortality and dose-limiting toxicity: the multicenter ONCO-BIVA study.ESMO open · 2024Observational
- Association between Physical Activity and Phase Angle Obtained via Bioelectrical Impedance Analysis in South Korean Adults Stratified by Sex.Nutrients · 2024Article
- Association between phase angle and diabetic peripheral neuropathy in Type 2 diabetes patients.Endocrine · 2024Article
- Methodology for integrated analysis of vector- and spectroscopic bioimpedance methods.Journal of electrical bioimpedance · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Patients with cancer experience dynamic and longitudinal changes in nutritional status and body composition along the disease trajectory. They often want to know about their outlook with regard to treatment outcomes and overall survival. One of the commonly used measures for body composition is bioelectrical impedance analysis (BIA). BIA is an easy-to-use, quick, inexpensive, noninvasive, and reproducible technique that is often incorporated in daily clinical practice. Phase angle (PA), which is derived from BIA, is an indicator of cell membrane health and integrity. Higher PA values reflect better cell function, higher muscle mass, and lower fat mass. PA is also thought to be a proxy of water distribution (ratio between extracellular water [ECW] and intracellular water [ICW]) and body cell mass. In this narrative review, we discuss studies examining the diagnostic and prognostic value of PA regarding nutritional status, body composition and physical function, complications of cancer treatments, overall survival, symptoms, and quality of life (QOL) in patients with cancer. The literature suggests that PA is moderately to strongly correlated with body composition and physical function but only weakly correlated with nutritional status, complications, survival, symptoms, and QOL. Furthermore, the PA cutoff values vary significantly according to study and patient population with the diversity of bioelectrical impedance technology and electrode composition and placement. Thus, PA has yet to be routinely incorporated into clinical practice for patients with cancer. Future research is needed to determine how to translate scientific understanding of PA to clinical practice.
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