Evidence map›Paper›PMID 36484897›Full record

ArticleAdvances in experimental medicine and biology2023

Leveraging Tissue Engineering for Skin Cancer Models.

Sumayah Oudda, Abdulla M Ali, Anna L Chien, Seungman Park

Open access · greenAbstract read
In one paragraph

Article in Advances in experimental medicine and biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Sumayah OuddaDepartment of Biology, Johns Hopkins University, Baltimore, MD, USA.
Abdulla M AliThe Thomas C. Jenkins Department of Biophysics, Johns Hopkins University, Baltimore, MD, USA.
Anna L ChienDepartment of Dermatology, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Seungman ParkDepartment of Mechanical Engineering, University of Nevada, Las Vegas, Las Vegas, NV, USA. seungman.park@unlv.edu.
Johns Hopkins University · USJohns Hopkins Medicine · USUniversity of Nevada, Las Vegas · US

Funding

Characterization of relation between tissue viscoelasticity and tumor progression in aging tissuesK25AG070286 · NIA · UNIVERSITY OF NEVADA LAS VEGAS · PI PARK, SEUNGMAN · 2021 to 2025
$734k
NIA NIH HHS K25 AG070286
6 · The paper itself

Abstract

Bioengineered in vitro three-dimensional (3D) skin model has emerged as a promising tool for recapitulating different types of skin cancer and performing pre-clinical tests. However, a full-thickness 3D model including the epidermis, dermis, and hypodermis layers is scarce despite its significance in human physiology and diverse biological processes. In this book chapter, an attempt has been made to summarize various skin cancer models, including utilized skin layers, materials, cell lines, specific treatments, and fabrication techniques for three types of skin cancer: melanoma, basal cell carcinoma (BCC), and squamous cell carcinoma (SCC). Subsequently, current limitations and future directions of skin cancer models are discussed. The knowledge of the current status of skin cancer models can provide various potential applications in cancer research and thus a more effective way for cancer treatment.

Indexed as

Basal Cell CarcinomaMelanomaSkin NeoplasmsHumansSkinTissue EngineeringBasal cell carcinoma (BCC)In vitro 3D modelMelanomaSkin cancerSquamous cell carcinoma (SCC)

Identifiers

PMID36484897
PMCPMC10316714
OpenAlexW4310937693

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.