Evidence map›Paper›PMID 36484810›Full record

ArticleKnee surgery, sports traumatology, arthroscopy : official journal of the ESSKA2023

Absorbable suture knots on the supraspinatus tendon prevent adverse effects of nonabsorbable suture knots in a rat model.

Hui Ben, Chunbing Luo, Jiaqi Cheng, Chu Hui Zeng, Youlang Zhou, In-Ho Jeon, Yucheng Sun

Abstract read
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Article in Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.2field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Hui Ben *Department of Hand Surgery, College of Medicine, Affiliated Hospital of Nantong University, University of Nantong, Nantong, 226001, Jiangsu, China.
Chunbing Luo *Department of Hand Surgery, College of Medicine, Affiliated Hospital of Nantong University, University of Nantong, Nantong, 226001, Jiangsu, China.
Jiaqi ChengDepartment of Spine Surgery, College of Medicine, Affiliated Hospital of Nantong University, University of Nantong, Nantong, China.
Chu Hui ZengDepartment of Radiology and Research Institute of Radiology, ASAN Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
Youlang ZhouDepartment of Hand Surgery, College of Medicine, Affiliated Hospital of Nantong University, University of Nantong, Nantong, 226001, Jiangsu, China.
In-Ho JeonDepartment of Orthopedic Surgery, ASAN Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
Yucheng SunDepartment of Hand Surgery, College of Medicine, Affiliated Hospital of Nantong University, University of Nantong, Nantong, 226001, Jiangsu, China. jacksunshoulder@gmail.com.ORCID http://orcid.org/0000-0001-5899-2792
Nantong University · CNUlsan College · KR

Funding

Affiliated Hospital of Nantong University No. Tdb2007Natural Science Foundation for the youth of Jiangsu Province No. BK20210843
6 · The paper itself

Abstract

purposeTo compare the absorbable and nonabsorbable suture knots on the tendon on bone-to-tendon healing during the early phase in a rat rotator cuff tear (RCT) model.

methodsFifty-two male Sprague-Dawley rats (10 weeks old; mean weight, 380 g) were used in this study, and 51 of them were randomly assigned into three groups: absorbable suture group (ASG, n = 22), nonabsorbable suture group (NSG, n = 22), and sham surgery group (SSG, n = 7), and the remaining rat was used to take surgical pictures. Bilateral supraspinatus tendon tears were created and repaired immediately in ASG and NSG. Three rats from ASG and NSG were killed for Western blot and histological evaluation at 3 days, 1 week, and 4 weeks after surgery. At 4 weeks, four rats from each group were killed for biomechanical test, and three rats from SSG were used for histological evaluation.

resultsAbsorbable suture knots on the tendon completely degraded at 4 weeks. However, nonabsorbable suture knots remained intact between the tendon and articular side. ASG showed a stronger inflammatory reaction at 3 days and 1 week, but a weaker reaction at 4 weeks as confirmed by gross observation and Western blot. Besides, ASG showed superior biomechanical properties in terms of maximum load to failure and stiffness at 4 weeks. Modified Bonar score revealed superior maturity for tissue healing in ASG to that in NSG at 4 weeks. Furthermore, inferior bone-to-tendon interface and weakest link formation were observed in NSG on histologic images.

conclusionAbsorbable suture knots on the tendon contributed to better mechanical properties compared with the nonabsorbable one after rotator cuff repair.

Indexed as

Rotator CuffRotator Cuff InjuriesAnimalsBiomechanical PhenomenaMaleRatsRats, Sprague-DawleySuturesTendonsAbsorbable suture knotBone-to-tendon healingEarly-stage inflammationNonabsorbable suture knotRotator cuff tear

Identifiers

PMID36484810
OpenAlexW4310960935

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.