Evidence map›Paper›PMID 36484794›Full record

ArticleJournal of molecular evolution2023

Very Low Rates of Spontaneous Gene Deletions and Gene Duplications in Dictyostelium discoideum.

Shelbi E Gill, Frédéric J J Chain

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of molecular evolution, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 citations in OpenAlex.

  1. The effect of spontaneous mutations onbioRxiv : the preprint server for biology · 2025
    Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Shelbi E GillDepartment of Biology, University of Massachusetts Lowell, Lowell, MA, 01854-2874, USA. shelbigill@me.com.
Frédéric J J ChainDepartment of Biology, University of Massachusetts Lowell, Lowell, MA, 01854-2874, USA. frederic_chain@uml.edu.ORCID 0000-0001-6169-7399
University of Massachusetts Lowell · US

Funding

The impact of polyQ-expansion and suppression of huntingtin-deficiency phenotypes in the model organism DictyosteliumR15GM134498 · NIGMS · UNIVERSITY OF MASSACHUSETTS LOWELL · PI CHAIN, FREDERIC · 2019 to 2019
$456k
NIGMS NIH HHS R15 GM134498NIH HHS 1R15GM134498
6 · The paper itself

Abstract

The study of spontaneous mutation rates has revealed a wide range of heritable point mutation rates across species, but there are comparatively few estimates for large-scale deletion and duplication rates. The handful of studies that have directly calculated spontaneous rates of deletion and duplication using mutation accumulation lines have estimated that genes are duplicated and deleted at orders of magnitude greater rates than the spontaneous point mutation rate. In our study, we tested whether spontaneous gene deletion and gene duplication rates are also high in Dictyostelium discoideum, a eukaryote with among the lowest point mutation rates (2.5 × 10

Indexed as

DictyosteliumGene DuplicationEukaryotaGene DeletionGenomeMutationCopy number variationDictyostelium discoideumGC contentMutationMutation accumulation experimentMutation rate

Identifiers

PMID36484794
PMCPMC9849192
OpenAlexW4310963315

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.