Evidence map›Paper›PMID 36484568›Full record

ArticleJournal of anatomy2023

MRI-based strain measurements reflect morphological changes following myocardial infarction: A study on the UK Biobank cohort.

Doyin S Mansell, Eva Sammut, Vito D Bruno, Raimondo Ascione, Jonathan C L Rodrigues, Harinderjit S Gill, Katharine H Fraser, Andrew N Cookson

Open access · hybridAbstract read
In one paragraph

Article in Journal of anatomy, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
  3. Relationships between heart shape, function, and disease in 38,858 UK biobank participants.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Doyin S MansellDepartment of Mechanical Engineering, University of Bath, Bath, UK.
Eva SammutDepartment of Translational Science, Bristol Heart Institute and Translational Biomedical Research Centre, Faculty of Health Science, Bristol Royal Infirmary, Level 7, University of Bristol, Bristol, UK.
Vito D BrunoDepartment of Translational Science, Bristol Heart Institute and Translational Biomedical Research Centre, Faculty of Health Science, Bristol Royal Infirmary, Level 7, University of Bristol, Bristol, UK.ORCID 0000-0002-8193-9559
Raimondo AscioneDepartment of Translational Science, Bristol Heart Institute and Translational Biomedical Research Centre, Faculty of Health Science, Bristol Royal Infirmary, Level 7, University of Bristol, Bristol, UK.ORCID 0000-0001-8045-5619
Jonathan C L RodriguesDepartment of Radiology, Royal United Hospitals Bath NHS Foundation Trust, Bath, UK.ORCID 0000-0003-2744-3509
Harinderjit S GillDepartment of Mechanical Engineering, University of Bath, Bath, UK.ORCID 0000-0002-7740-2062
Katharine H FraserDepartment of Mechanical Engineering, University of Bath, Bath, UK.ORCID 0000-0002-7828-1354
Andrew N CooksonDepartment of Mechanical Engineering, University of Bath, Bath, UK.ORCID 0000-0002-5382-5116
University of Bath · GBBristol Royal Infirmary · GBRoyal United Hospital Bath NHS Trust · GB

Funding

Medical Research Council MC_PC_17228Medical Research Council MC_QA137853Medical Research Council MR/L012723/1
6 · The paper itself

Abstract

In a porcine experimental model of myocardial infarction, a localised, layer-specific, circumferential left ventricular strain metric has been shown to indicate chronic changes in ventricular function post-infarction more strongly than ejection fraction. This novel strain metric might therefore provide useful prognostic information clinically. In this study, existing clinical volume indices, global strains, and the novel, layer-specific strain were calculated for a large human cohort to assess variations in ventricular function and morphology with age, sex, and health status. Imaging and health data from the UK Biobank were obtained, including healthy volunteers and those with a history of cardiovascular illness. In total, 710 individuals were analysed and stratified by age, sex and health. Significant differences in all strain metrics were found between healthy and unhealthy populations, as well as between males and females. Significant differences in basal circumferential strain and global circumferential strain were found between healthy males and females, with males having smaller absolute values for both (all

Indexed as

Myocardial InfarctionVentricular Function, LeftAnimalsBiological Specimen BanksFemaleHumansMagnetic Resonance ImagingMaleStroke VolumeSwineUnited Kingdom

Identifiers

PMID36484568
PMCPMC9773168
OpenAlexW4310953818

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.